Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21913733 | 0.89 | GABRA1 (0.41) | CYP3A4TDP1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL8936346 | 0.86 | CYP1A2 (0.36) | CYP3A4TDP1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL7006142 | 0.81 | ALDH1A1 (0.77) | CYP3A4TDP1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL9760797 | 0.79 | ALDH1A1 (0.43) | ALDH1A1MAPTTSHRMAPK1LMNA | |
| Benzyl Alcohol SCHEMBL28300920 | 0.77 | TSHR (0.45) | ALDH1A1TSHRGABRA1GABRB2SIGMAR1 | |
| SCHEMBL820893 | 0.77 | CYP3A4 (0.44) | CYP3A4TDP1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL7008498 | 0.77 | TDP1 (0.63) | CYP3A4TDP1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL7013209 | 0.77 | ALDH1A1 (0.63) | CYP3A4TDP1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL7009406 | 0.77 | ALDH1A1 (0.63) | CYP3A4TDP1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL14562915 | 0.77 | CYP3A4 (0.47) | CYP3A4TDP1ALDH1A1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1186595-B1 | Diaryl-p-phenylenediamine disulfides | GOODYEAR TIRE & RUBBER (US) | 2003-11-26 | — | — | EP | disclosed |
| US-6627686-B1 | Mixture with rubber; oxidation resistance; tires, rolls, conveyor belts, footwear | THE GOODYEAR TIRE & RUBBER COMPANY | 2003-09-30 | — | — | US | disclosed |
| EP-1186595-A1 | Diaryl-p-phenylenediamine disulfides | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2002-03-13 | — | — | EP | disclosed |
| EP-0700963-B1 | Polymeric N-aryl substituted and N-alkaryl substituted diphenyldiamines | GOODYEAR TIRE & RUBBER (US) | 1999-04-14 | — | — | EP | disclosed |
| US-5726248-A | ANTIOXIDANTS FOR DIENE POLYMERS WITH HIGH MOLECULAR WEIGHTS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1998-03-10 | — | — | US | disclosed |
| EP-0700963-A1 | Polymeric N-aryl substituted and N-alkaryl substituted diphenyldiamines | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1996-03-13 | — | — | EP | disclosed |