Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13377362 | 0.80 | GABRA1 (0.38) | CYP3A4ALDH1A1TDP1L3MBTL1CYP1A2 | |
| SCHEMBL820809 | 0.78 | L3MBTL1 (0.51) | CYP3A4ALDH1A1TDP1L3MBTL1CYP1A2 | |
| SCHEMBL14562915 | 0.78 | CYP3A4 (0.47) | CYP3A4ALDH1A1TDP1L3MBTL1CYP1A2 | |
| SCHEMBL6933727 | 0.77 | CYP3A4 (0.57) | CYP3A4ALDH1A1TDP1L3MBTL1CYP1A2 | |
| SCHEMBL7028664 | 0.71 | GABRA1 (0.43) | CYP3A4ALDH1A1TDP1L3MBTL1CYP1A2 | |
| SCHEMBL22748315 | 0.70 | GABRA1 (0.46) | CYP3A4CYP1A2TSHRGABRA1GABRG2 | |
| SCHEMBL29088787 | 0.70 | GABRA1 (0.41) | CYP3A4CYP1A2TSHRGABRA1GABRG2 | |
| SCHEMBL7671735 | 0.69 | CA1 (0.44) | CYP3A4ALDH1A1TDP1CYP1A2TSHR | |
| SCHEMBL13377297 | 0.68 | CA1 (0.40) | CYP3A4ALDH1A1TDP1L3MBTL1CYP1A2 | |
| SCHEMBL66227 | 0.67 | GABRA1 (0.57) | CYP3A4L3MBTL1CYP1A2CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110275783-A1 | Nitro compound, amine compound and polyamide derived therefrom | NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) | 2011-11-10 | — | — | US | claimed |
| US-20110275781-A1 | Nitro compound, amine compound, polyimide and polyimide copolymer derived therefrom | NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) | 2011-11-10 | — | — | US | claimed |
| US-8492508-B2 | Nitro compound, amine compound, polyimide and polyimide copolymer derived therefrom | NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) | 2013-07-23 | — | — | US | disclosed |
| US-8367797-B2 | Nitro compound, amine compound and polyamide derived therefrom | NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) | 2013-02-05 | — | — | US | disclosed |
| US-20110275783-A1 | Nitro compound, amine compound and polyamide derived therefrom | NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) | 2011-11-10 | — | — | US | disclosed |
| US-20110275781-A1 | Nitro compound, amine compound, polyimide and polyimide copolymer derived therefrom | NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) | 2011-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275783-A1 | Nitro compound, amine compound and polyamide derived therefrom | NOS2, NOS1, NOS3 | CYP3A4 1179/4885ALDH1A1 2358/4885TDP1 1336/4885 |
| US-20110275781-A1 | Nitro compound, amine compound, polyimide and polyimide copolymer derived therefrom | THEM6, NOS2, NOS1 | CYP3A4 1102/4885ALDH1A1 2644/4885TDP1 2136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.