Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6936002 | 0.82 | BCHE (0.41) | LMNABCHESMN1; SMN2POLB | |
| Bromide SCHEMBL27893551 | 0.81 | BCHE (0.40) | LMNABCHESMN1; SMN2POLB | |
| SCHEMBL31571120 | 0.75 | ALDH1A1 (0.37) | BCHESMN1; SMN2KDM1AHTTPOLB | |
| SCHEMBL9305366 | 0.75 | ALDH1A1 (0.37) | BCHESMN1; SMN2KDM1AHTTPOLB | |
| SCHEMBL11070811 | 0.74 | LMNA (0.60) | LMNASMN1; SMN2POLB | |
| SCHEMBL22781187 | 0.73 | KDM4E (0.49) | LMNAKDM4ESMN1; SMN2HSD17B10POLB | |
| SCHEMBL4968281 | 0.69 | LMNA (0.52) | LMNASMN1; SMN2KDM1AHTTHSD17B10 | |
| SCHEMBL3386305 | 0.69 | BCHE (0.41) | BCHEKDM4ESMN1; SMN2HSD17B10POLB | |
| SCHEMBL9359079 | 0.69 | GSK3B (0.44) | LMNABCHESMN1; SMN2KDM1A | |
| SCHEMBL8834714 | 0.69 | CACNA1C (0.40) | LMNABCHESMN1; SMN2HTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808163-B1 | USE OF THIAZOLIUM COMPOUNDS FOR PREVENTING AND REVERSING THE FORMATION OF ADVANCED GLYCOSYLATION ENDPRODUCTS | ALTEON INC (US) | 2003-07-23 | — | — | EP | claimed |
| US-6440749-B1 | ADMINISTERING A THIAZOLE COMPOUND | ALTEON. INC. | 2002-08-27 | — | — | US | claimed |