SCHEMBL6933789

SCHEMBL6933789

COC(C)CN=C(N)N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21790700 0.78
SCHEMBL23311441 0.76 DDAH1 (0.38)
SCHEMBL1793339 0.73
SCHEMBL4095379 0.70
SCHEMBL22355183 0.70
SCHEMBL7077041 0.69
SCHEMBL3588935 0.67
SCHEMBL8198467 0.67 MAPT (0.32)
SCHEMBL10299229 0.67 NOS2 (0.34)
SCHEMBL21789708 0.65 NOS2 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1115143-C Cosmetic composition KAO CORP (JP) 2003-07-23 CN disclosed
EP-0805674-B1 SKIN AND HAIR COSMETIC COMPOSITIONS KAO CORP (JP) 2003-03-12 EP disclosed
US-6348200-B1 OXYALKYLAMIDE OR AMINE DERIVATIVES;AT LEAST ONE OF POLYHYDRIC ALCOHOLS, OR VEGETABLE EXTRACTS, OR ORGANIC ACIDS; IMPROVES WATER-RETAINING ABILITY OF HORNY LAYER, CURES ROUGHNESS AND PREVENTS WRINKLES KAO CORPORATION (JP) 2002-02-19 US disclosed
CN-1065527-C Guanidine derivatives, process for producing granidine derivatives and cosmetics containing guanidine derivatives KAO CORP (JP) 2001-05-09 CN disclosed
US-6187955-B1 A MOISTURIZER FOR SOFTENING SKINS; USEFUL AS COMPONENTS OF COSMETIC FORMULATIONS KAO CORPORATION (JP) 2001-02-13 US disclosed
US-5723133-A GUANIDINE WITH ORGANIC ACID FOR SKIN SOFTENING KAO CORPORATION (JP) 1998-03-03 US disclosed
CN-1166135-A Cosmetic compsns. KAO CORP (JP) 1997-11-26 CN disclosed
EP-0805674-A1 SKIN AND HAIR COSMETIC COMPOSITIONS Kao Corporation (JP) 1997-11-12 EP disclosed
WO-1997014401-A1 SKIN AND HAIR COSMETIC COMPOSITIONS KAO CORPORATION (JP) 1997-04-24 WO disclosed
CN-1127249-A Guanidine derivatives, process for producing granidine derivatives and cosmetics containing guanidine derivatives KAO CORP (JP) 1996-07-24 CN disclosed