Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6934396 | 0.85 | ALDH1A1 (0.40) | MEN1KMT2ACYP2D6ALDH1A1TSHR | |
| SCHEMBL6930357 | 0.80 | ALOX12 (0.35) | ALDH1A1GAAKDM4EL3MBTL1ALOX12 | |
| SCHEMBL6931558 | 0.77 | ELANE (0.37) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL6934817 | 0.76 | ELANE (0.35) | MEN1KMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL6727748 | 0.74 | MAPT (0.43) | MEN1KMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL6935664 | 0.72 | MAPT (0.40) | MEN1KMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL6932814 | 0.71 | ELANE (0.37) | MEN1KMT2AMAPTALDH1A1TSHR | |
| SCHEMBL6932528 | 0.69 | GAA (0.38) | CYP1A2CYP2C19MAPTALDH1A1GAA | |
| SCHEMBL6932809 | 0.69 | GAA (0.35) | MEN1KMT2ACYP1A2CYP2C19MAPT | |
| SCHEMBL8489871 | 0.69 | KMT2A (0.40) | MEN1KMT2ACYP1A2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903342-B1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | OREAL (FR) | 2003-12-17 | — | — | EP | claimed |
| EP-0903342-A1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | L'OREAL (FR) | 1999-03-24 | — | — | EP | claimed |
| EP-0903342-B1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | OREAL (FR) | 2003-12-17 | — | — | EP | disclosed |
| EP-0903342-A1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | L'OREAL (FR) | 1999-03-24 | — | — | EP | disclosed |