Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 5/20 | 0.49 |
| ▸ | SRC | P12931 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 3/20 | 0.39 |
| ▸ | CES2 | O00748 | 3/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27474029 | 0.85 | CES1 (0.56) | CES1SRCTSHRTDP1ALDH1A1 | |
| SCHEMBL8332006 | 0.80 | CES1 (0.60) | CES1SRCTSHRTDP1ALDH1A1 | |
| SCHEMBL27908747 | 0.79 | CES1 (0.46) | CES1SRCTSHRTDP1ALDH1A1 | |
| SCHEMBL11566993 | 0.78 | CES1 (0.44) | CES1SRCTSHRTDP1ALDH1A1 | |
| Benzophenone SCHEMBL27630083 | 0.76 | CES1 (0.55) | CES1SRCTSHRTDP1ALDH1A1 | |
| SCHEMBL869019 | 0.74 | CES1 (0.73) | CES1SRCTSHRTDP1ALDH1A1 | |
| SCHEMBL11866869 | 0.73 | CES1 (0.47) | CES1SRCTSHRTDP1ALDH1A1 | |
| SCHEMBL16613087 | 0.73 | CES1 (0.44) | CES1SRCTSHRTDP1ALDH1A1 | |
| SCHEMBL3661644 | 0.72 | CES1 (0.60) | CES1SRCTSHRTDP1ALDH1A1 | |
| SCHEMBL10090157 | 0.72 | CES1 (0.60) | CES1SRCTSHRTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363869-A2 | PROCESS FOR THE PREPARATION OF ALKYL BENZOYLACRYLATES | Clariant (France) S.A. (FR) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002067847-A2 | PROCESS FOR THE PREPARATION OF ALKYL BENZOYLACRYLATES | CLARIANT (FRANCE) (FR) | 2002-09-06 | — | — | WO | disclosed |