Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 2/20 | 0.38 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5832283 | 0.84 | AKT1 (0.51) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL6934142 | 0.84 | FBP1 (0.35) | MEN1KMT2ALMNAMAPTPOLB | |
| SCHEMBL5831228 | 0.82 | MEN1 (0.59) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL5831678 | 0.82 | AKT1 (0.44) | MEN1KMT2ALMNAAKT1 | |
| SCHEMBL5830785 | 0.81 | HSD11B1 (0.42) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL5831645 | 0.77 | MEN1 (0.55) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL5830489 | 0.76 | HSD11B1 (0.38) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL5832095 | 0.74 | ATM (0.62) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL5831313 | 0.73 | USP36 (0.48) | MEN1KMT2A | |
| SCHEMBL5831270 | 0.72 | USP36 (0.62) | MEN1KMT2ANPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004113310-A1 | USE OF AN INHIBITOR OF 11-B-HYDROXYSTEROID DEHYDROGENASE TYPE 1 COMPOUNDS FOR PROMOTING WOUND HEALING | BIOVITRUM AB (SE) | 2004-12-29 | — | — | WO | disclosed |