Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.31 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27934957 | 0.79 | ALDH1A1 (0.44) | ALDH1A1LMNAHSD17B10FAAHTSHR | |
| SCHEMBL6235031 | 0.77 | — | — | |
| SCHEMBL6235022 | 0.77 | — | — | |
| SCHEMBL6940725 | 0.72 | LMNA (0.41) | LMNATSHR | |
| SCHEMBL6940728 | 0.72 | LMNA (0.41) | LMNATSHR | |
| SCHEMBL5288 | 0.71 | — | — | |
| Acetic Acid SCHEMBL27488764 | 0.69 | ALDH1A1 (0.38) | ALDH1A1LMNAHSD17B10FAAHSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4967118 | 0.69 | — | — | |
| SCHEMBL28458016 | 0.68 | — | — | |
| SCHEMBL9311644 | 0.67 | ALDH1A1 (0.43) | ALDH1A1LMNAHSD17B10FAAHCHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979814-B1 | Improved synthesis of haloformimine compounds | ROHM & HAAS (US) | 2003-10-22 | — | — | EP | claimed |
| US-6207863-B1 | MAINTAINING A PH BETWEEN 2 AND 5 DURING THE HALOGENATION OF FORMIMINES GREATLY INCREASES THE YIELDS OF HALOFORMIMINES AND GREATLY DECREASES THE RATE OF BY-PRODUCT FORMATION. | ROHM AND HAAS COMPANY | 2001-03-27 | — | — | US | claimed |
| EP-0979814-A1 | Improved synthesis of haloformimine compounds | ROHM AND HAAS COMPANY (US) | 2000-02-16 | — | — | EP | claimed |
| EP-0979814-B1 | Improved synthesis of haloformimine compounds | ROHM & HAAS (US) | 2003-10-22 | — | — | EP | disclosed |
| US-6207863-B1 | MAINTAINING A PH BETWEEN 2 AND 5 DURING THE HALOGENATION OF FORMIMINES GREATLY INCREASES THE YIELDS OF HALOFORMIMINES AND GREATLY DECREASES THE RATE OF BY-PRODUCT FORMATION. | ROHM AND HAAS COMPANY | 2001-03-27 | — | — | US | disclosed |
| EP-0979814-A1 | Improved synthesis of haloformimine compounds | ROHM AND HAAS COMPANY (US) | 2000-02-16 | — | — | EP | disclosed |