Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 6/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 5/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 5/20 | 0.35 |
| ▸ | KDM5C | P41229 | 4/20 | 0.35 |
| ▸ | KDM6B | O15054 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.31 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6940728 | 1.00 | LMNA (0.41) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| SCHEMBL6934174 | 0.72 | ALDH1A1 (0.37) | LMNATSHR | |
| SCHEMBL2400956 | 0.67 | — | — | |
| SCHEMBL2050853 | 0.67 | ALDH1A1 (0.36) | LMNAHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL2050851 | 0.67 | ALDH1A1 (0.36) | LMNAHDAC3HDAC1HDAC2HDAC8 | |
| Succinic Acid SCHEMBL9455643 | 0.66 | TSHR (0.62) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| SCHEMBL27629925 | 0.66 | — | — | |
| Succinic Acid SCHEMBL28787942 | 0.66 | LMNA (0.65) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL28787941 | 0.66 | LMNA (0.65) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL15051622 | 0.66 | LMNA (0.65) | LMNASLC15A2EGLN1ALKBH5SUCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979814-B1 | Improved synthesis of haloformimine compounds | ROHM & HAAS (US) | 2003-10-22 | — | — | EP | claimed |