Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PKLR | P30613 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5887723 | 0.84 | SIRT1 (0.61) | MAPTPOLBHSD17B10TSHRLMNA | |
| SCHEMBL6934406 | 0.83 | HSD17B10 (0.53) | MAPTPOLBHSD17B10TSHRLMNA | |
| SCHEMBL6934354 | 0.81 | SIRT1 (0.53) | SMN1; SMN2MAPTPOLBLMNAL3MBTL1 | |
| SCHEMBL4440485 | 0.81 | HSD17B10 (0.64) | SMN1; SMN2MAPTPOLBHSD17B10TSHR | |
| SCHEMBL9150092 | 0.80 | SMN1; SMN2 (0.49) | SMN1; SMN2POLBL3MBTL1SIRT1KMT2A | |
| SCHEMBL9150088 | 0.80 | SMN1; SMN2 (0.49) | SMN1; SMN2POLBL3MBTL1SIRT1KMT2A | |
| SCHEMBL9151841 | 0.80 | SMN1; SMN2 (0.49) | SMN1; SMN2POLBL3MBTL1SIRT1KMT2A | |
| SCHEMBL6632593 | 0.80 | SIRT1 (0.70) | SMN1; SMN2MAPTHSD17B10TSHRLMNA | |
| SCHEMBL28189180 | 0.79 | SIRT1 (0.54) | MAPTPOLBHSD17B10TSHRLMNA | |
| SCHEMBL4802025 | 0.79 | MAPT (0.55) | SMN1; SMN2MAPTPOLBHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086079-B1 | DERIVATIVES OF HYDROXYPHENYLSULFANYLBENZOIC AND HYDROXYPHENYLSULFANYLARYLACETIC ACIDS | LECIVA A S (CZ) | 2003-05-07 | — | — | EP | disclosed |
| US-6303612-B1 | USED AS ANTIINFLAMMATORY AND/OR ANTIASTHMATIC AGENTS | LECIVA, A.S. (CZ) | 2001-10-16 | — | — | US | disclosed |
| EP-1086079-A1 | DERIVATIVES OF HYDROXYPHENYLSULFANYLBENZOIC AND HYDROXYPHENYLSULFANYLARYLACETIC ACIDS | Leciva, A.S. (CZ) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999067208-A1 | DERIVATIVES OF HYDROXYPHENYLSULFANYLBENZOIC AND HYDROXYPHENYLSULFANYLARYLACETIC ACIDS | LECIVA, A.S. (CZ) | 1999-12-29 | — | — | WO | disclosed |