SCHEMBL6934397

SCHEMBL6934397

CCOCCC[CH]C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8162489 0.94 CES1 (0.36) ALDH1A1CES2CES1
SCHEMBL6938892 0.88 ALDH1A1 (0.36) ALDH1A1
SCHEMBL6941222 0.86 CES2 (0.33) CES2CES1
SCHEMBL6937666 0.86 TSHR (0.43) CES2CES1
SCHEMBL6937877 0.85 CES1 (0.44) ALDH1A1CES2CES1
SCHEMBL6932051 0.83 CES1 (0.47) ALDH1A1CES2CES1
SCHEMBL6934662 0.83 CES1 (0.47) ALDH1A1CES2CES1
SCHEMBL6934486 0.83 CES1 (0.47) ALDH1A1CES2CES1
SCHEMBL6937495 0.83 CES1 (0.47) ALDH1A1CES2CES1
SCHEMBL6936686 0.83 CES1 (0.47) ALDH1A1CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0962445-B1 Acetylene compound, liquid crystal composition and liquid crystal element MITSUI CHEMICALS INC (JP) 2003-02-26 EP disclosed
US-6217793-B1 Acetylene compound, liquid crystal composition and liquid crystal element MITSUI CHEMICALS, INC. (JP) 2001-04-17 US disclosed
EP-0962445-A1 Acetylene compound, liquid crystal composition and liquid crystal element Mitsui Chemicals, Inc. (JP) 1999-12-08 EP disclosed
EP-0518636-A1 Liquid crystal compounds and compositions SANYO CHEMICAL INDUSTRIES LTD. (JP) 1992-12-16 EP disclosed
EP-0517498-A1 Liquid crystal compounds and compositions SANYO CHEMICAL INDUSTRIES LTD. (JP) 1992-12-09 EP disclosed
EP-0500210-A2 Liquid crystal compounds and compositions SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1992-08-26 EP disclosed
EP-0409634-A2 Liquid crystal compounds and optically active compounds SANYO CHEMICAL INDUSTRIES LTD. (JP) 1991-01-23 EP disclosed