Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | DHFR | P00374 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | ADK | P55263 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29424973 | 0.74 | MAPT (0.58) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1128621 | 0.74 | MAPT (0.58) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL15958624 | 0.73 | GRM5 (0.48) | KDM4EALDH1A1HPGDADORA2AAPP | |
| SCHEMBL557769 | 0.73 | GRM4 (0.44) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27158469 | 0.72 | ADK (0.48) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29913169 | 0.72 | ADK (0.48) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27158140 | 0.72 | GRM5 (0.49) | MAPTKDM4EALDH1A1HPGDPLAU | |
| SCHEMBL27158029 | 0.72 | ADK (0.48) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29444102 | 0.71 | MAPT (1.00) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL503252 | 0.71 | MAPT (1.00) | MAPTKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030207886-A1 | Preparation containing quinoxaline derivatives | MERCK PATENT GMBH (DE) | 2003-11-06 | — | — | US | disclosed |
| EP-1267819-A2 | PREPARATION CONTAINING QUINOXALINE DERIVATIVES | MERCK PATENT GmbH (DE) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001068047-A2 | PREPARATION CONTAINING QUINOXALINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2001-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030207886-A1 | Preparation containing quinoxaline derivatives | CUTA, XPA, NQO2 | MAPT 2455/4885KDM4E 467/4885ALDH1A1 1898/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.