SCHEMBL6934600

SCHEMBL6934600

[CH2]CCCOCC(CCCCC)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.35
PLA2G2C Q5R387 4/20 0.35
HTT P42858 1/20 0.34
CES2 O00748 1/20 0.34
CES1 P23141 1/20 0.34
CYP3A4 P08684 2/20 0.33
SPHK1 Q9NYA1 1/20 0.32
CYP2C19 P33261 2/20 0.31
CYP1A2 P05177 1/20 0.31
PRKD3 O94806 1/20 0.31
PRKCG P05129 1/20 0.31
PRKCB P05771 1/20 0.31
PRKCA P17252 1/20 0.31
PRKCH P24723 1/20 0.31
PRKCI P41743 1/20 0.31
PRKCE Q02156 1/20 0.31
PRKCQ Q04759 1/20 0.31
PRKCZ Q05513 1/20 0.31
PRKCD Q05655 1/20 0.31
PRKD1 Q15139 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6936858 0.94 USP2 (0.40) USP2PLA2G2CHTTCES2CES1
SCHEMBL6937315 0.94 USP2 (0.40) USP2PLA2G2CHTTCES2CES1
SCHEMBL6936264 0.86 FDPS (0.34) CES2CES1CYP1A2FDPSHSD17B10
SCHEMBL28322781 0.84 USP2 (0.46) USP2PLA2G2CHTTCES2CES1
SCHEMBL6937501 0.83 USP2 (0.35) USP2PLA2G2CHTTCYP3A4SPHK1
SCHEMBL6940861 0.82 CYP3A4 (0.30) CYP3A4
SCHEMBL7850734 0.80 FDPS (0.37) FDPS
SCHEMBL6933916 0.78 USP2 (0.40) USP2PLA2G2CHTTSPHK1PRKD3
SCHEMBL6939630 0.78 USP2 (0.40) USP2PLA2G2CHTTSPHK1PRKD3
SCHEMBL6939913 0.76 USP2 (0.33) USP2PLA2G2CHTTCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0962445-B1 Acetylene compound, liquid crystal composition and liquid crystal element MITSUI CHEMICALS INC (JP) 2003-02-26 EP disclosed
EP-0751133-B1 Pyrimidine compound, and liquid crystal composition and liquid crystal element using the same MITSUI CHEMICALS INC (JP) 2001-09-12 EP disclosed
US-6217793-B1 Acetylene compound, liquid crystal composition and liquid crystal element MITSUI CHEMICALS, INC. (JP) 2001-04-17 US disclosed
EP-0962445-A1 Acetylene compound, liquid crystal composition and liquid crystal element Mitsui Chemicals, Inc. (JP) 1999-12-08 EP disclosed
US-5770108-A HIGH SPEED RESPONSE, MOLECULAR ORIENTATION, HIGH CONTRAST, RECEPTIVITY MITSUI TOATSU CHEMICALS, INC. (JP) 1998-06-23 US disclosed
EP-0751133-A1 Pyrimidine compound, and liquid crystal composition and liquid crystal element using the same MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1997-01-02 EP disclosed