SCHEMBL6936858

SCHEMBL6936858

[CH2]CCCCCCCOCC(CCCCC)C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.40
HTT P42858 1/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
PLA2G2C Q5R387 4/20 0.39
SPHK1 Q9NYA1 1/20 0.36
PRKD3 O94806 1/20 0.36
PRKCG P05129 1/20 0.36
PRKCB P05771 1/20 0.36
PRKCA P17252 1/20 0.36
PRKCH P24723 1/20 0.36
PRKCI P41743 1/20 0.36
PRKCE Q02156 1/20 0.36
PRKCQ Q04759 1/20 0.36
PRKCZ Q05513 1/20 0.36
PRKCD Q05655 1/20 0.36
PRKD1 Q15139 1/20 0.36
LPAR1 Q92633 6/20 0.35
LPAR3 Q9UBY5 6/20 0.35
LPAR5 Q9H1C0 4/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6937315 1.00 USP2 (0.40) USP2HTTCES2CES1PLA2G2C
SCHEMBL6934600 0.94 USP2 (0.35) USP2HTTCES2CES1PLA2G2C
SCHEMBL28322781 0.89 USP2 (0.46) USP2HTTCES2CES1PLA2G2C
SCHEMBL6939630 0.84 USP2 (0.40) USP2HTTPLA2G2CSPHK1PRKD3
SCHEMBL6933916 0.84 USP2 (0.40) USP2HTTPLA2G2CSPHK1PRKD3
SCHEMBL6936703 0.83 USP2 (0.33) USP2HTTCES2CES1PLA2G2C
SCHEMBL6939913 0.83 USP2 (0.33) USP2HTTCES2CES1PLA2G2C
SCHEMBL6936264 0.83 FDPS (0.34) CES2CES1HSD17B10
SCHEMBL11254160 0.79 FDPS (0.40)
SCHEMBL28686486 0.78 CES2 (0.44) USP2HTTCES2CES1PLA2G2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0962445-B1 Acetylene compound, liquid crystal composition and liquid crystal element MITSUI CHEMICALS INC (JP) 2003-02-26 EP disclosed
EP-0751133-B1 Pyrimidine compound, and liquid crystal composition and liquid crystal element using the same MITSUI CHEMICALS INC (JP) 2001-09-12 EP disclosed
US-6217793-B1 Acetylene compound, liquid crystal composition and liquid crystal element MITSUI CHEMICALS, INC. (JP) 2001-04-17 US disclosed
EP-0962445-A1 Acetylene compound, liquid crystal composition and liquid crystal element Mitsui Chemicals, Inc. (JP) 1999-12-08 EP disclosed
US-5770108-A HIGH SPEED RESPONSE, MOLECULAR ORIENTATION, HIGH CONTRAST, RECEPTIVITY MITSUI TOATSU CHEMICALS, INC. (JP) 1998-06-23 US disclosed
EP-0751133-A1 Pyrimidine compound, and liquid crystal composition and liquid crystal element using the same MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1997-01-02 EP disclosed