SCHEMBL6936264

SCHEMBL6936264

[CH2]COCC(CCCCC)C(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.34
FAAH O00519 8/20 0.31
OPRM1 P35372 1/20 0.31
CES1 P23141 6/20 0.31
CES2 O00748 3/20 0.31
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6934600 0.86 USP2 (0.35) FDPSCES1CES2CYP1A2HSD17B10
SCHEMBL6936858 0.83 USP2 (0.40) CES1CES2HSD17B10
SCHEMBL6937315 0.83 USP2 (0.40) CES1CES2HSD17B10
SCHEMBL6938950 0.81 FDPS (0.34) FDPSOPRM1
SCHEMBL6937556 0.79
SCHEMBL28322781 0.79 USP2 (0.46) CES1CES2MEN1KMT2A
SCHEMBL3802952 0.79 FDPS (0.43) FDPSFAAHOPRM1CES1CES2
SCHEMBL7850734 0.78 FDPS (0.37) FDPSFAAHOPRM1
SCHEMBL23981574 0.77 FDPS (0.47) FDPSFAAHOPRM1CES1CES2
SCHEMBL21308386 0.77 FDPS (0.47) FDPSFAAHOPRM1CES1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0962445-B1 Acetylene compound, liquid crystal composition and liquid crystal element MITSUI CHEMICALS INC (JP) 2003-02-26 EP disclosed
EP-0751133-B1 Pyrimidine compound, and liquid crystal composition and liquid crystal element using the same MITSUI CHEMICALS INC (JP) 2001-09-12 EP disclosed
US-6217793-B1 Acetylene compound, liquid crystal composition and liquid crystal element MITSUI CHEMICALS, INC. (JP) 2001-04-17 US disclosed
EP-0962445-A1 Acetylene compound, liquid crystal composition and liquid crystal element Mitsui Chemicals, Inc. (JP) 1999-12-08 EP disclosed
US-5770108-A HIGH SPEED RESPONSE, MOLECULAR ORIENTATION, HIGH CONTRAST, RECEPTIVITY MITSUI TOATSU CHEMICALS, INC. (JP) 1998-06-23 US disclosed
EP-0751133-A1 Pyrimidine compound, and liquid crystal composition and liquid crystal element using the same MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1997-01-02 EP disclosed