SCHEMBL6934666

SCHEMBL6934666

COc1cc(S(=O)(=O)O)[c]cc1S(=O)(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.39
MAPT P10636 2/20 0.39
KMT2A Q03164 2/20 0.39
LMNA P02545 1/20 0.39
GSK3B P49841 1/20 0.36
PKM P14618 2/20 0.36
TRPV4 Q9HBA0 1/20 0.35
MPL P40238 1/20 0.34
TSHR P16473 3/20 0.33
GAA P10253 3/20 0.33
NPBWR1 P48145 1/20 0.33
KDM4E B2RXH2 3/20 0.33
NPSR1 Q6W5P4 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
GLA P06280 1/20 0.32
MAPK1 P28482 2/20 0.32
POLB P06746 1/20 0.32
CDC25A P30304 1/20 0.32
CDC25B P30305 1/20 0.32
HIF1A Q16665 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10504821 0.86 ALDH1A1 (0.39) ALDH1A1MAPTKMT2ALMNAGSK3B
SCHEMBL7046102 0.82 ALDH1A1 (0.39) ALDH1A1MAPTKMT2ALMNAGSK3B
SCHEMBL9163475 0.82 MAOB (0.37) ALDH1A1MAPTKMT2ALMNAMPL
SCHEMBL6633299 0.77 LMNA (0.31) LMNAHIF1AHPGDHSD17B10
SCHEMBL1888725 0.76 ALDH1A1 (0.51) ALDH1A1MAPTKMT2ALMNAGSK3B
SCHEMBL5049711 0.76 BRD4 (0.39) CASRTP53
SCHEMBL9774295 0.74 ALDH1A1 (0.50) ALDH1A1MAPTKMT2ALMNAGSK3B
SCHEMBL4409480 0.73 TTR (0.37) ALDH1A1MAPTKMT2APKMTSHR
SCHEMBL11324905 0.72
SCHEMBL10508320 0.72 BRD4 (0.36) LMNAPOLBHIF1ACASRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1054043-A2 Orange and scarlet coloured mixtures of reactive dyes DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2000-11-22 EP claimed
EP-0712841-B1 Process for the preparation of 3(N-aryl-amino)-propyl-2'-sulfatoethylsulfonyl compounds DYSTAR TEXTILFARBEN GMBH & CO (DE) 1999-01-13 EP claimed
US-5777111-A DERIVATIVES OF ARYL SUBSTITUTED 1,3-OXAZINES HOECHST AKTIENGESELLSCHAFT (DE) 1998-07-07 US claimed
US-5672738-A REACTING AN AROMATIC SUBSTITUTED CYCLIC CARBAMATE WITH 2-MERCAPTETHANOL IN PRESENCE OF A BASIC CATALYST HOECHST AKTIENGESELLSCHAFT (DE) 1997-09-30 US claimed
EP-0712841-A1 Process for the preparation of 3(N-aryl-amino)-propyl-2'-sulfatoethylsulfonyl compounds HOECHST AKTIENGESELLSCHAFT (DE) 1996-05-22 EP claimed
EP-0303081-B1 WATER SOLUBLE DISAZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DE) 1992-01-02 EP claimed
US-5055565-A Fiber-reactive dyes HOECHST AKTIENGESELLSCHAFT (DE) 1991-10-08 US claimed
EP-0303081-A1 Water soluble disazo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1989-02-15 EP claimed
EP-1000983-B1 Dye mixture, process for its preparation and its use DYSTAR TEXTILFARBEN GMBH & CO (DE) 2003-10-22 EP disclosed
EP-0765965-B1 Process for deying synthetic fibrous polyamid materials DYSTAR TEXTILFARBEN GMBH & CO (DE) 2003-06-04 EP disclosed
WO-2003006560-A2 AQUEOUS INK FORMULATIONS FOR INKJET PRINTING DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2003-01-23 WO disclosed
EP-1173522-A1 DEEP NAVY DYE MIXTURES OF FIBER-REACTIVE AZO DYES AND A METHOD FOR THEIR PREPARATION AS WELL AS A PROCESS FOR DYEING HYDROXY- AND/OR CARBOXAMIDO-CONTAINING FIBERS DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2002-01-23 EP disclosed
EP-0950692-B1 Azo compounds, process for their preparation and their use as fiber-reactive dyes DYSTAR TEXTILFARBEN GMBH & CO (DE) 2001-10-17 EP disclosed
EP-1127923-A2 Water-soluble fibre-reactive dyestuffs, process for their preparation and their use DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2001-08-29 EP disclosed
US-4748236-A Azo dyestuffs having sulpho ortho to azo bridge and containing two triazine reactive groups BAYER AKTIENGESELLSCHAFT (DE) 1988-05-31 US disclosed
EP-0050266-B1 REACTIVE DISAZO DYES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN DYEING AND PRINTING MATERIALS THAT CONTAIN HYDROXYL AND/OR NITROGEN BAYER AG (DE) 1984-10-03 EP disclosed
US-4418015-A Phthalocyanine reactive dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1983-11-29 US disclosed
EP-0053320-A2 Process for the preparation of phthalocyanin compounds BAYER AG (DE) 1982-06-09 EP disclosed
EP-0047863-A2 Reactive phthalocyanine hyes, process for their preparation and their use in dyeing materials containing hydroxyle groups and/or nitrogen BAYER AG (DE) 1982-03-24 EP disclosed
US-4280956-A CONTAINING SULFONAMIDE GROUPS BAYER AKTIENGESELLSCHAFT (DE) 1981-07-28 US disclosed