Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL12 | P48061 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 5/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6934681 | 1.00 | CXCL12 (0.38) | CXCL12MAOBCYP1A1CYP1B1TDP1 | |
| SCHEMBL6932505 | 0.89 | LMNA (0.35) | CXCL12MAOBCYP1B1HTR1ASLC6A2 | |
| SCHEMBL6935659 | 0.89 | LMNA (0.35) | CXCL12MAOBCYP1B1HTR1ASLC6A2 | |
| SCHEMBL9643228 | 0.81 | CXCL12 (0.34) | CXCL12MAOBCYP1A1CYP1B1TDP1 | |
| SCHEMBL9643233 | 0.81 | CXCL12 (0.34) | CXCL12MAOBCYP1A1CYP1B1TDP1 | |
| SCHEMBL7862126 | 0.78 | SMN1; SMN2 (0.32) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7862124 | 0.78 | TTR (0.32) | CXCL12HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7862130 | 0.77 | CXCL12 (0.32) | CXCL12 | |
| SCHEMBL6935483 | 0.75 | MAPK14 (0.39) | MAPK14 | |
| SCHEMBL6935487 | 0.75 | MAPK14 (0.39) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131273-B1 | 1,4-DIARYL-2-FLUORO-1-BUTEN-3-OL COMPOUNDS AND THEIR USE IN THE PREPARATION OF 1,4-DIARYL-2-FLUORO-1,3-BUTADIENE AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS | BASF AG (DE) | 2003-10-22 | — | — | EP | claimed |
| US-6342642-B1 | DEHYDROXYLATION OF HALOBUTENOL COMPOUNDS TO FORM BUTADIENES | BASF AKTIENGESELLSCHAFT (DE) | 2002-01-29 | — | — | US | claimed |
| EP-1202948-B1 | PROCESSES FOR THE PREPARATION OF 2-ARYLVINYL ALKYL ETHER AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS | BASF AG (DE) | 2003-12-10 | — | — | EP | disclosed |
| EP-1131273-B1 | 1,4-DIARYL-2-FLUORO-1-BUTEN-3-OL COMPOUNDS AND THEIR USE IN THE PREPARATION OF 1,4-DIARYL-2-FLUORO-1,3-BUTADIENE AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS | BASF AG (DE) | 2003-10-22 | — | — | EP | disclosed |
| US-6342642-B1 | DEHYDROXYLATION OF HALOBUTENOL COMPOUNDS TO FORM BUTADIENES | BASF AKTIENGESELLSCHAFT (DE) | 2002-01-29 | — | — | US | disclosed |
| US-6291721-B1 | REACTING 2-ARYL ALDEHYDE COMPOUND WITH ALCOHOL OR HEATING ACETAL COMPOUND IN PRESENCE OF APROTIC SOLVENT TO PRODUCE2-ARYLVINYL ETHER COMPOUND | AMERICAN CYANAMID CO. | 2001-09-18 | — | — | US | disclosed |