Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL12 | P48061 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9643233 | 1.00 | CXCL12 (0.34) | CXCL12MAPK14CYP1A1CYP1B1MAOB | |
| SCHEMBL10466636 | 0.89 | FFAR4 (0.34) | MAPK14PARP10 | |
| SCHEMBL10466635 | 0.89 | FFAR4 (0.34) | MAPK14PARP10 | |
| SCHEMBL9540404 | 0.89 | LMNA (0.36) | CXCL12PARP10PTGDR2 | |
| SCHEMBL9540399 | 0.89 | LMNA (0.36) | CXCL12PARP10PTGDR2 | |
| SCHEMBL6934678 | 0.81 | CXCL12 (0.38) | CXCL12MAPK14CYP1A1CYP1B1MAOB | |
| SCHEMBL6934681 | 0.81 | CXCL12 (0.38) | CXCL12MAPK14CYP1A1CYP1B1MAOB | |
| SCHEMBL9642455 | 0.73 | ALOX5 (0.40) | MEN1KMT2APTGS1 | |
| SCHEMBL9642457 | 0.73 | ALOX5 (0.40) | MEN1KMT2APTGS1 | |
| SCHEMBL9494663 | 0.72 | PARP10 (0.36) | MAPK14MEN1KMT2APARP10FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0357610-B1 | INSECTICIDAL CYCLOPROPYL-SUBSTITUTED DI(ARYL) COMPOUNDS | FMC Corporation (US) | 1992-09-16 | — | — | EP | disclosed |
| EP-0357610-A1 | INSECTICIDAL CYCLOPROPYL-SUBSTITUTED DI(ARYL) COMPOUNDS. | FMC CORP (US) | 1990-03-14 | — | — | EP | disclosed |
| US-4808762-A | Insecticidal cyclopropyl-substituted di(aryl) compounds | FMC CORPORATION (US) | 1989-02-28 | — | — | US | disclosed |
| WO-1988008416-A1 | INSECTICIDAL CYCLOPROPYL-SUBSTITUTED DI(ARYL) COMPOUNDS | FMC CORPORATION (US) | 1988-11-03 | — | — | WO | disclosed |