Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | MGLL | Q99685 | 3/20 | 0.37 |
| ▸ | FAAH | O00519 | 3/20 | 0.37 |
| ▸ | GBA1 | P04062 | 3/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6933521 | 0.69 | GBA1 (0.38) | ALOX5PTGS1PTGS2MGLLFAAH | |
| SCHEMBL7607806 | 0.67 | MGLL (0.40) | ALOX5PTGS1PTGS2MGLLFAAH | |
| SCHEMBL10407766 | 0.67 | ALOX5 (0.40) | ALOX5PTGS1PTGS2MGLLFAAH | |
| SCHEMBL8493925 | 0.67 | ALOX5 (0.47) | ALOX5PTGS1PTGS2MGLLFAAH | |
| SCHEMBL8776115 | 0.66 | ALOX5 (0.39) | ALOX5PTGS1PTGS2MGLLFAAH | |
| SCHEMBL11499061 | 0.65 | MGLL (0.43) | ALOX5PTGS1PTGS2MGLLFAAH | |
| SCHEMBL10915954 | 0.61 | GBA1 (0.42) | ALOX5PTGS1PTGS2MGLLFAAH | |
| SCHEMBL8716131 | 0.61 | ALOX5 (0.45) | ALOX5PTGS1PTGS2MGLLFAAH | |
| SCHEMBL20376257 | 0.61 | ALOX5 (0.45) | ALOX5PTGS1PTGS2MGLLFAAH | |
| SCHEMBL6550307 | 0.61 | MGLL (0.50) | ALOX5PTGS1PTGS2MGLLFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903342-B1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | OREAL (FR) | 2003-12-17 | — | — | EP | disclosed |
| EP-0903342-A1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | L'OREAL (FR) | 1999-03-24 | — | — | EP | disclosed |