Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 4/20 | 0.38 |
| ▸ | FAAH | O00519 | 4/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.34 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | GBA1 | P04062 | 2/20 | 0.33 |
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16325248 | 0.80 | MEN1 (0.43) | ALOX5FAAHALDH1A1MEN1KMT2A | |
| SCHEMBL11499488 | 0.75 | MGLL (0.50) | ALOX5MGLLFAAHPTGS1PTGS2 | |
| SCHEMBL10407766 | 0.73 | ALOX5 (0.40) | ALOX5MGLLFAAHPTGS1PTGS2 | |
| SCHEMBL11499061 | 0.71 | MGLL (0.43) | ALOX5MGLLFAAHPTGS1PTGS2 | |
| SCHEMBL11498881 | 0.69 | GBA1 (0.38) | ALOX5MGLLFAAHPTGS1PTGS2 | |
| SCHEMBL7607806 | 0.69 | MGLL (0.40) | ALOX5MGLLFAAHPTGS1PTGS2 | |
| SCHEMBL11499149 | 0.67 | ALOX5 (0.45) | ALOX5MGLLFAAHPTGS1PTGS2 | |
| SCHEMBL1885530 | 0.67 | ALOX5 (0.49) | ALOX5MGLLFAAHPTGS1PTGS2 | |
| SCHEMBL9229895 | 0.66 | ALDH1A1 (0.52) | ALOX5MGLLFAAHPTGS1PTGS2 | |
| SCHEMBL11498912 | 0.65 | ALOX5 (0.56) | ALOX5MGLLFAAHPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640076-B1 | TRIAZOLINONE RING FORMATION IN TERT-BUTANOL | FMC CORP (US) | 1997-11-26 | — | — | EP | disclosed |
| US-5440045-A | Triazolinone ring formation in tert-butanol | FMC CORPORATION (US) | 1995-08-08 | — | — | US | disclosed |
| EP-0640076-A4 | TRIAZOLINONE RING FORMATION IN TERT-BUTANOL. | FMC CORP (US) | 1995-04-12 | — | — | EP | disclosed |
| EP-0640076-A1 | TRIAZOLINONE RING FORMATION IN TERT-BUTANOL | FMC CORPORATION (US) | 1995-03-01 | — | — | EP | disclosed |
| WO-1993023382-A1 | TRIAZOLINONE RING FORMATION IN TERT-BUTANOL | FMC CORPORATION (US) | 1993-11-25 | — | — | WO | disclosed |
| US-5256793-A | Triazolinone ring formation in tert-butanol | FMC CORPORATION (US) | 1993-10-26 | — | — | US | disclosed |