Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | GLP1R | P43220 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.42 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.42 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | STK10 | O94804 | 1/20 | 0.40 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6930303 | 0.92 | LMNA (0.44) | CYP3A4CYP2C9MAPTMEN1KMT2A | |
| SCHEMBL6932694 | 0.91 | MAPT (0.42) | CYP3A4CYP2C9MAPTLMNANPSR1 | |
| SCHEMBL6933451 | 0.85 | CNR1 (0.44) | CNR1CYP3A4MAPTSCN9AMEN1 | |
| SCHEMBL6928225 | 0.85 | CNR1 (0.44) | CNR1CYP3A4MAPTSCN9AMEN1 | |
| SCHEMBL6931599 | 0.84 | KMT2A (0.46) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL8495131 | 0.84 | ACHE (0.41) | CYP3A4CYP2C9MAPTMEN1KMT2A | |
| SCHEMBL6935197 | 0.81 | KDM4E (0.40) | CYP2C9MAPTSCN9AMEN1KMT2A | |
| SCHEMBL6932816 | 0.80 | CES2 (0.44) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6930299 | 0.79 | BACE1 (0.49) | CYP3A4CYP2C9LMNAGAA | |
| SCHEMBL6935629 | 0.79 | APP (0.49) | MAPTMEN1KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903342-B1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | OREAL (FR) | 2003-12-17 | — | — | EP | disclosed |
| US-5958382-A | ARTIFICIAL TANNING AND/OR COLORING OF HUMAN SKIN AND/OR HAIR | SOCIETE L'OREAL S.A. (FR) | 1999-09-28 | — | — | US | disclosed |
| EP-0903342-A1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | L'OREAL (FR) | 1999-03-24 | — | — | EP | disclosed |