Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22781186 | 0.70 | KDM4E (0.39) | KAT2BKDM4ESMN1; SMN2PPARGTSHR | |
| SCHEMBL6350872 | 0.66 | KAT2B (0.38) | KAT2BKDM4ESMN1; SMN2PPARG | |
| SCHEMBL6350869 | 0.66 | KAT2B (0.38) | KAT2BKDM4ESMN1; SMN2PPARG | |
| SCHEMBL6935663 | 0.61 | KAT2B (0.36) | KAT2BKDM4ESMN1; SMN2PPARGTSHR | |
| Bromide SCHEMBL2955263 | 0.60 | KAT2B (0.35) | KAT2BKDM4ESMN1; SMN2TSHR | |
| SCHEMBL15387077 | 0.60 | — | — | |
| SCHEMBL4438410 | 0.58 | RIPK1 (0.31) | — | |
| SCHEMBL7575787 | 0.58 | SMN1; SMN2 (0.47) | SMN1; SMN2 | |
| SCHEMBL11069013 | 0.58 | KDM4E (0.39) | KAT2BKDM4ESMN1; SMN2PPARGTSHR | |
| Hydrochloric Acid SCHEMBL13719077 | 0.57 | SMN1; SMN2 (0.46) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808163-B1 | USE OF THIAZOLIUM COMPOUNDS FOR PREVENTING AND REVERSING THE FORMATION OF ADVANCED GLYCOSYLATION ENDPRODUCTS | ALTEON INC (US) | 2003-07-23 | — | — | EP | claimed |
| US-6440749-B1 | ADMINISTERING A THIAZOLE COMPOUND | ALTEON. INC. | 2002-08-27 | — | — | US | claimed |
| US-6007865-A | FOR INHIBITING AND REVERSING NONENZYMATIC CROSS-LINKING (PROTEIN AGING), TREATING KIDNEY DAMAGE AND TREATING COMPLICATIONS OF DIABETES, PREVENTING FOOD SPOILAGE | ALTEON INC. | 1999-12-28 | — | — | US | claimed |