Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6939766 | 0.75 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2HPGDMAPK1HSD17B10 | |
| SCHEMBL6937570 | 0.73 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2HPGDMAPK1HSD17B10 | |
| SCHEMBL6940069 | 0.70 | TDP1 (0.37) | ALDH1A1TDP1MAPK1RAB9AL3MBTL1 | |
| SCHEMBL6939514 | 0.70 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2TDP1MEN1KMT2A | |
| SCHEMBL11369132 | 0.68 | TDP1 (0.35) | ALDH1A1SMN1; SMN2TDP1MEN1KMT2A | |
| SCHEMBL581530 | 0.67 | PDE10A (0.33) | TDP1 | |
| SCHEMBL11217150 | 0.64 | TDP1 (0.38) | ALDH1A1SMN1; SMN2TDP1MEN1KMT2A | |
| SCHEMBL8536797 | 0.64 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2TDP1MEN1KMT2A | |
| SCHEMBL9279970 | 0.62 | L3MBTL1 (0.35) | ALDH1A1SMN1; SMN2TDP1MEN1KMT2A | |
| SCHEMBL4387705 | 0.62 | SMN1; SMN2 (0.44) | ALDH1A1SMN1; SMN2TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1147477-C | Novel allylthiopyridazine derivative and process for producing the same | ��ʽ���纺����ҩ | 2004-04-28 | — | — | CN | disclosed |
| EP-1058681-B1 | NOVEL ALLYLTHIOPYRIDAZINE DERIVATIVES AND PROCESS FOR PREPARING THE SAME | SEOUL PHARM CO LTD (KR) | 2003-05-07 | — | — | EP | disclosed |
| CN-1285825-A | Novel allylthiopyridazine derivative and process for producing the same | SEOUL PHARM CO LTD (KR) | 2001-02-28 | — | — | CN | disclosed |
| EP-1058681-A1 | NOVEL ALLYLTHIOPYRIDAZINE DERIVATIVES AND PROCESS FOR PREPARING THE SAME | Seoul Pharm. Co., Ltd. (KR) | 2000-12-13 | — | — | EP | disclosed |
| US-5942511-A | PROTECTION OF HUMAN TISSUE FROM RADIATION | Kwon, Soon Kyoung (KR) | 1999-08-24 | — | — | US | disclosed |
| WO-1999036407-A1 | NOVEL ALLYLTHIOPYRIDAZINE DERIVATIVES AND PROCESS FOR PREPARING THE SAME | SEOUL PHARM. CO., LTD. (KR) | 1999-07-22 | — | — | WO | disclosed |