Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6937349 | 0.76 | L3MBTL1 (0.35) | TDP1L3MBTL1ALDH1A1TSHRMAPK1 | |
| SCHEMBL6937153 | 0.74 | ALDH1A1 (0.33) | TDP1L3MBTL1ALDH1A1TSHR | |
| SCHEMBL15623942 | 0.71 | — | — | |
| SCHEMBL587789 | 0.71 | MAPK1 (0.37) | ALDH1A1MAPK1HTTLMNA | |
| SCHEMBL30101051 | 0.71 | MAPK1 (0.37) | ALDH1A1MAPK1HTTLMNA | |
| SCHEMBL6935201 | 0.70 | ALDH1A1 (0.42) | TDP1L3MBTL1ALDH1A1TSHRMAPK1 | |
| SCHEMBL24379631 | 0.69 | NSD2 (0.35) | MAPK1HTT | |
| SCHEMBL30932816 | 0.69 | NSD2 (0.35) | MAPK1HTT | |
| SCHEMBL26163823 | 0.69 | NSD2 (0.35) | MAPK1HTT | |
| SCHEMBL28934784 | 0.69 | NSD2 (0.35) | MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1058681-B1 | NOVEL ALLYLTHIOPYRIDAZINE DERIVATIVES AND PROCESS FOR PREPARING THE SAME | SEOUL PHARM CO LTD (KR) | 2003-05-07 | — | — | EP | disclosed |
| US-5942511-A | PROTECTION OF HUMAN TISSUE FROM RADIATION | Kwon, Soon Kyoung (KR) | 1999-08-24 | — | — | US | disclosed |