Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL204249 | 1.00 | TRPA1 (0.44) | TRPA1NFE2L2CYP1A2CYP2C19HSD17B10 | |
| SCHEMBL7170865 | 1.00 | TRPA1 (0.44) | TRPA1NFE2L2CYP1A2CYP2C19HSD17B10 | |
| SCHEMBL29358897 | 1.00 | TRPA1 (0.44) | TRPA1NFE2L2CYP1A2CYP2C19HSD17B10 | |
| SCHEMBL7170869 | 1.00 | TRPA1 (0.44) | TRPA1NFE2L2CYP1A2CYP2C19HSD17B10 | |
| SCHEMBL28354139 | 1.00 | TRPA1 (0.44) | TRPA1NFE2L2CYP1A2CYP2C19HSD17B10 | |
| SCHEMBL8159487 | 0.99 | BACE1 (0.43) | TRPA1NFE2L2CYP1A2CYP2C19HSD17B10 | |
| SCHEMBL8159482 | 0.99 | BACE1 (0.43) | TRPA1NFE2L2CYP1A2CYP2C19HSD17B10 | |
| SCHEMBL10358886 | 0.89 | SNCA (0.45) | TRPA1NFE2L2BACE1SNCALMNA | |
| SCHEMBL9308756 | 0.89 | NFE2L2 (0.42) | TRPA1NFE2L2CYP1A2CYP2C19BACE1 | |
| SCHEMBL10358885 | 0.89 | SNCA (0.45) | TRPA1NFE2L2BACE1SNCALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178826-B2 | Fungicides | SYNGENTA LTD (GB) | 2003-04-09 | — | — | EP | disclosed |
| EP-0178826-B1 | FUNGICIDES | ZENECA LIMITED (GB) | 1991-12-18 | — | — | EP | disclosed |