SCHEMBL204249

SCHEMBL204249

CO/C=C(/C(=O)OC)c1ccccc1C=Cc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.44
NFE2L2 Q16236 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C19 P33261 1/20 0.44
HSD17B10 Q99714 1/20 0.44
CAPN1 P07384 1/20 0.42
BACE1 P56817 1/20 0.41
SNCA P37840 4/20 0.40
LMNA P02545 1/20 0.40
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6935295 1.00 TRPA1 (0.44) TRPA1NFE2L2CYP1A2CYP2C19HSD17B10
SCHEMBL7170865 1.00 TRPA1 (0.44) TRPA1NFE2L2CYP1A2CYP2C19HSD17B10
SCHEMBL29358897 1.00 TRPA1 (0.44) TRPA1NFE2L2CYP1A2CYP2C19HSD17B10
SCHEMBL7170869 1.00 TRPA1 (0.44) TRPA1NFE2L2CYP1A2CYP2C19HSD17B10
SCHEMBL28354139 1.00 TRPA1 (0.44) TRPA1NFE2L2CYP1A2CYP2C19HSD17B10
SCHEMBL8159487 0.99 BACE1 (0.43) TRPA1NFE2L2CYP1A2CYP2C19HSD17B10
SCHEMBL8159482 0.99 BACE1 (0.43) TRPA1NFE2L2CYP1A2CYP2C19HSD17B10
SCHEMBL10358886 0.89 SNCA (0.45) TRPA1NFE2L2BACE1SNCALMNA
SCHEMBL9308756 0.89 NFE2L2 (0.42) TRPA1NFE2L2CYP1A2CYP2C19BACE1
SCHEMBL10358885 0.89 SNCA (0.45) TRPA1NFE2L2BACE1SNCALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12464971-B2 Sowing device and method for treating seeds during planting SYNGENTA CROP PROTECTION AG (CH) 2025-11-11 US disclosed
CN-108430980-B Microbicidal oxadiazole derivatives 先正达参股股份有限公司 2022-09-02 CN disclosed
CN-111093372-B Microbicidal quinoline (thio) carboxamide derivatives 先正达参股股份有限公司 2022-05-27 CN disclosed
CN-111050558-B Microbicidal quinoline (thio) carboxamide derivatives 先正达参股股份有限公司 2022-05-27 CN disclosed
CN-108137517-B Microbicidal oxadiazole derivatives 先正达参股股份有限公司 2022-04-12 CN disclosed
CN-109071522-B Microbicidal oxadiazole derivatives 先正达参股股份有限公司 2022-04-12 CN disclosed
CN-108779109-B Microbicidal oxadiazole derivatives 先正达参股股份有限公司 2022-03-11 CN disclosed
CN-108137570-B Microbicidal oxadiazole derivatives 先正达参股股份有限公司 2022-01-28 CN disclosed
CN-113873886-A Overcoat compositions 特洛伊公司 2021-12-31 CN disclosed
US-11185074-B2 Microbiocidal quinoline (thio)carboxamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2021-11-30 US disclosed
US-20040258768-A1 An aqueous solution of injectable particles of sparingly soluble copper salts not easily leached, yet with sustained microbiocidal and insecticidal effectiveness; impregnation by injection OSMOSE, INC 2004-12-23 US disclosed
US-20030134857-A1 Synergistic insecticide mixtures UHR HERMANN (DE) 2003-07-17 US disclosed
EP-1313368-A1 SYNERGISTIC BIOCIDAL COMPOSITION THOR GmbH (DE) 2003-05-28 EP disclosed
EP-0178826-B2 Fungicides SYNGENTA LTD (GB) 2003-04-09 EP disclosed
WO-2002015693-A9 SYNERGISTIC BIOCIDAL COMPOSITION THOR GMBH (DE) 2002-06-06 WO disclosed
WO-2002015693-A1 SYNERGISTIC BIOCIDAL COMPOSITION THOR GMBH (DE) 2002-02-28 WO disclosed
US-6197799-B1 PLANT SAFENING AGENTS; PRESERVATIVES BAYER AKTIENGESELLSCHAFT (DE) 2001-03-06 US disclosed
EP-0820370-A1 TIMBER PRESERVATIVE CONTAINING A COPPER COMPOUND BAYER AG (DE) 1998-01-28 EP disclosed
WO-1996032235-A1 TIMBER PRESERVATIVE CONTAINING A COPPER COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1996-10-17 WO disclosed
EP-0178826-B1 FUNGICIDES ZENECA LIMITED (GB) 1991-12-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030134857-A1 Synergistic insecticide mixtures CHRM3, CHRNA5, CHRNA2 TRPA1 269/4885NFE2L2 3924/4885CYP1A2 487/4885
US-11185074-B2 Microbiocidal quinoline (thio)carboxamide derivatives IFNG, TLR1, IDO1 TRPA1 477/4885NFE2L2 1858/4885CYP1A2 233/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.