Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3964323 | 0.99 | ALDH1A1 (0.54) | ALDH1A1LMNAKDM4EGSK3BMAPT | |
| SCHEMBL6103661 | 0.86 | CA12 (0.46) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| Bromide SCHEMBL3846883 | 0.85 | CA12 (0.45) | ALDH1A1LMNAKDM4EMAPTNPC1 | |
| SCHEMBL6939128 | 0.85 | ALDH1A1 (0.44) | ALDH1A1LMNAKDM4EGSK3BMAPT | |
| SCHEMBL6935010 | 0.85 | RAB9A (0.43) | ALDH1A1LMNAKDM4EGSK3BMAPT | |
| SCHEMBL6937918 | 0.85 | ALDH1A1 (0.41) | ALDH1A1LMNAKDM4EGSK3BMAPT | |
| Bromide SCHEMBL3957516 | 0.84 | RAB9A (0.45) | ALDH1A1LMNAKDM4EGSK3BMAPT | |
| Bromide SCHEMBL2946957 | 0.84 | MAPT (0.45) | ALDH1A1LMNAKDM4EGSK3BMAPT | |
| Bromide SCHEMBL2947505 | 0.84 | ALDH1A1 (0.43) | ALDH1A1LMNAKDM4EGSK3BMAPT | |
| Bromide SCHEMBL3845606 | 0.82 | ALDH1A1 (0.60) | ALDH1A1LMNAKDM4EGSK3BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808163-B1 | USE OF THIAZOLIUM COMPOUNDS FOR PREVENTING AND REVERSING THE FORMATION OF ADVANCED GLYCOSYLATION ENDPRODUCTS | ALTEON INC (US) | 2003-07-23 | — | — | EP | claimed |
| US-6440749-B1 | ADMINISTERING A THIAZOLE COMPOUND | ALTEON. INC. | 2002-08-27 | — | — | US | claimed |