Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3957516 | 0.99 | RAB9A (0.45) | RAB9AKMT2ALMNAMEN1TP53 | |
| SCHEMBL6939128 | 0.87 | ALDH1A1 (0.44) | RAB9AKMT2ALMNAMEN1MAPK1 | |
| SCHEMBL6937918 | 0.87 | ALDH1A1 (0.41) | RAB9AKMT2ALMNAMEN1SMN1; SMN2 | |
| Bromide SCHEMBL2946957 | 0.86 | MAPT (0.45) | RAB9AKMT2ALMNAMEN1MAPK1 | |
| Bromide SCHEMBL2947505 | 0.86 | ALDH1A1 (0.43) | RAB9AKMT2ALMNAMEN1TP53 | |
| SCHEMBL6935377 | 0.85 | ALDH1A1 (0.52) | RAB9AKMT2ALMNAMEN1GSK3B | |
| SCHEMBL3849473 | 0.84 | ALDH1A1 (0.43) | KMT2ALMNAMEN1MAPK1SMN1; SMN2 | |
| Bromide SCHEMBL3964323 | 0.84 | ALDH1A1 (0.54) | RAB9AKMT2ALMNAMEN1GSK3B | |
| Bromide SCHEMBL3850356 | 0.82 | MAPT (0.37) | RAB9AKMT2ALMNAMEN1MAPK1 | |
| Bromide SCHEMBL3853609 | 0.81 | THRA (0.45) | RAB9AKMT2ALMNAMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808163-B1 | USE OF THIAZOLIUM COMPOUNDS FOR PREVENTING AND REVERSING THE FORMATION OF ADVANCED GLYCOSYLATION ENDPRODUCTS | ALTEON INC (US) | 2003-07-23 | — | — | EP | claimed |
| US-6440749-B1 | ADMINISTERING A THIAZOLE COMPOUND | ALTEON. INC. | 2002-08-27 | — | — | US | claimed |