Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | PTAFR | P25105 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL2955255 | 0.98 | ALDH1A1 (0.50) | ALDH1A1TSHRKMT2AUSP2KDM4E | |
| Bromide SCHEMBL6432443 | 0.79 | ALDH1A1 (0.39) | ALDH1A1KMT2AMEN1LMNAHPGD | |
| SCHEMBL14008412 | 0.77 | ALDH1A1 (0.55) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2953104 | 0.76 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL17817035 | 0.75 | NAAA (0.50) | ALDH1A1TSHRUSP2LMNAGMNN | |
| SCHEMBL12534300 | 0.71 | KMT2A (0.50) | ALDH1A1TSHRKMT2AUSP2KDM4E | |
| SCHEMBL8390045 | 0.71 | ALDH1A1 (0.64) | ALDH1A1KMT2AKDM4ELMNAMAPT | |
| Bromide SCHEMBL3853715 | 0.70 | ALDH1A1 (0.67) | ALDH1A1KMT2AKDM4ELMNAMAPT | |
| Hydrochloric Acid SCHEMBL5848674 | 0.69 | HSP90AA1 (0.50) | ALDH1A1KMT2AUSP2KDM4EMEN1 | |
| Bromide SCHEMBL9080240 | 0.69 | KMT2A (0.53) | ALDH1A1TSHRKMT2AUSP2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808163-B1 | USE OF THIAZOLIUM COMPOUNDS FOR PREVENTING AND REVERSING THE FORMATION OF ADVANCED GLYCOSYLATION ENDPRODUCTS | ALTEON INC (US) | 2003-07-23 | — | — | EP | claimed |
| US-6440749-B1 | ADMINISTERING A THIAZOLE COMPOUND | ALTEON. INC. | 2002-08-27 | — | — | US | claimed |