Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.60 |
| ▸ | CTSB | P07858 | 5/20 | 0.60 |
| ▸ | CTSL | P07711 | 5/20 | 0.60 |
| ▸ | CTSS | P25774 | 5/20 | 0.60 |
| ▸ | REN | P00797 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14020888 | 0.85 | CTSK (0.62) | CTSKCTSBCTSLCTSSREN | |
| SCHEMBL4800376 | 0.83 | CTSK (0.67) | CTSKCTSBCTSLCTSSCASP1 | |
| SCHEMBL4622697 | 0.83 | CTSK (0.67) | CTSKCTSBCTSLCTSSCASP1 | |
| SCHEMBL28546631 | 0.83 | CTSK (0.67) | CTSKCTSBCTSLCTSSCASP1 | |
| SCHEMBL6663697 | 0.83 | CTSK (0.62) | CTSKCTSBCTSLCTSSREN | |
| SCHEMBL25289369 | 0.82 | CTSK (0.63) | CTSKCTSBCTSLCTSSCASP1 | |
| SCHEMBL25286871 | 0.82 | CTSK (0.63) | CTSKCTSBCTSLCTSSREN | |
| SCHEMBL25247153 | 0.82 | CTSK (0.63) | CTSKCTSBCTSLCTSSREN | |
| SCHEMBL25289368 | 0.82 | CTSK (0.63) | CTSKCTSBCTSLCTSSCASP1 | |
| SCHEMBL25282430 | 0.82 | CTSK (0.65) | CTSKCTSBCTSLCTSSCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030138864-A1 | Method for identifying an enzyme to design anti-cancer compounds | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030138864-A1 | Method for identifying an enzyme to design anti-cancer compounds | RNASE1, GUSB, DPEP1 | CTSK 333/4885CTSB 316/4885CTSL 526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.