Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | PRKCI | P41743 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27949813 | 0.88 | MAPT (0.48) | CASP1TSHRPRKCIMAPTKDM4E | |
| SCHEMBL710621 | 0.83 | TSHR (0.50) | CASP1TSHRPRKCIMAPTKDM4E | |
| SCHEMBL6497283 | 0.83 | CYP3A4 (0.45) | CASP1PRKCIMAPTKDM4EGAA | |
| SCHEMBL6152292 | 0.82 | TYR (0.46) | CASP1TSHRPRKCIMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL16087335 | 0.81 | TSHR (0.48) | CASP1TSHRPRKCIMAPTKDM4E | |
| SCHEMBL33926 | 0.81 | PRKCI (0.59) | CASP1TSHRPRKCIMAPTKDM4E | |
| SCHEMBL8761713 | 0.81 | TSHR (0.48) | CASP1TSHRPRKCIMAPTKDM4E | |
| SCHEMBL13183889 | 0.80 | PRKCI (0.42) | CASP1TSHRPRKCIMAPTKDM4E | |
| SCHEMBL23412633 | 0.79 | RECQL (0.58) | CASP1TSHRPRKCIMAPTKDM4E | |
| SCHEMBL9790056 | 0.79 | CASP1 (0.46) | CASP1TSHRPRKCIMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2678037-B1 | BRANCHED LINKER FOR PROTEIN DRUG CONJUGATES | LONZA AG (CH) | 2014-12-03 | — | — | EP | claimed |
| CN-115850449-A | Antibodies and conjugates | 苏州智核生物医药科技有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-114957156-A | Compound containing benzoxazine structure, resin composition, prepreg and electric copper clad laminate, and preparation method and application thereof | 成都科宜高分子科技有限公司 | 2022-08-30 | — | — | CN | disclosed |
| EP-3040451-B1 | REACTION PRODUCTS OF AMINO ACIDS AND EPOXIES | ROHM & HAAS ELECT MAT (US) | 2018-07-25 | — | — | EP | disclosed |
| WO-2016115360-A1 | C-MYC LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | COFERON, INC. (US) | 2016-07-21 | — | — | WO | disclosed |
| CN-103384534-B | Branched linker for protein drug conjugates | LONZA LTD. (CH) | 2015-09-30 | — | — | CN | disclosed |
| CN-104906592-A | Branched linker for protein drug conjugates | LONZA AG | 2015-09-16 | — | — | CN | disclosed |
| WO-2015106292-A1 | BCR-ABL TYROSINE-KINASE LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | COFERON, INC. (US) | 2015-07-16 | — | — | WO | disclosed |
| WO-2015081280-A1 | BROMODOMAIN LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION | COFERON, INC. (US) | 2015-06-04 | — | — | WO | disclosed |
| US-20140243286-A1 | BROMODOMAIN LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | COFERON, INC. (US) | 2014-08-28 | — | — | US | disclosed |
| US-20140243286-A1 | BROMODOMAIN LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | COFERON, INC. (US) | 2014-08-28 | — | — | US | disclosed |
| CN-103384534-A | Branched linker for protein drug conjugates | LONZA AG | 2013-11-06 | — | — | CN | disclosed |
| WO-2013033270-A2 | BROMODOMAIN LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | COFERON, INC. (US) | 2013-03-07 | — | — | WO | disclosed |
| US-8361935-B2 | Metal free crosslinking of galactomannan | SCHLUMBERGER TECHNOLOGY CORPORATION (US) | 2013-01-29 | — | — | US | disclosed |
| EP-0876135-B1 | DYEING AGENT FOR DYEING KERATIN FIBRES | WELLA AG (DE) | 2003-04-09 | — | — | EP | disclosed |
| EP-0876135-A1 | DYEING AGENT FOR DYEING KERATIN FIBRES | Wella Aktiengesellschaft (DE) | 1998-11-11 | — | — | EP | disclosed |
| WO-1998017233-A1 | DYEING AGENT FOR DYEING KERATIN FIBRES | WELLA AKTIENGESELLSCHAFT (DE) | 1998-04-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140243286-A1 | BROMODOMAIN LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | BRDT, BRD4, BRD1 | CASP1 3291/4885TSHR 2940/4885PRKCI 1020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.