SCHEMBL6152292

SCHEMBL6152292

Nc1ccc(CCO)c(O)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.46
TSHR P16473 1/20 0.45
CASP1 P29466 1/20 0.45
PRKCI P41743 1/20 0.41
MAPT P10636 4/20 0.41
KDM4E B2RXH2 4/20 0.41
ALDH1A1 P00352 2/20 0.41
GAA P10253 2/20 0.41
CYP3A4 P08684 1/20 0.41
ESR2 Q92731 1/20 0.41
PTPN1 P18031 1/20 0.41
TDP1 Q9NUW8 3/20 0.40
MEN1 O00255 2/20 0.40
RAD52 P43351 2/20 0.40
RECQL P46063 2/20 0.40
KMT2A Q03164 2/20 0.40
ACHE P22303 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
PDE10A Q9Y233 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23412633 0.84 RECQL (0.58) TYRTSHRCASP1PRKCIMAPT
SCHEMBL29780621 0.84 RECQL (0.58) TYRTSHRCASP1PRKCIMAPT
SCHEMBL146272 0.83 PRKCI (0.55) TSHRCASP1PRKCIMAPTKDM4E
SCHEMBL6961023 0.83 PRKCI (0.37) TYRTSHRCASP1PRKCIMAPT
SCHEMBL6935962 0.82 CASP1 (0.48) TYRTSHRCASP1PRKCIMAPT
SCHEMBL2384003 0.81 ADRA2B (0.45) TSHRMAPTKDM4EGAATDP1
SCHEMBL3048700 0.81 TYR (0.50) TYRTSHRCASP1PRKCIMAPT
SCHEMBL213571 0.80 CASP1 (0.39) TSHRCASP1PRKCIMAPTKDM4E
SCHEMBL29835039 0.80 CASP1 (0.39) TSHRCASP1PRKCIMAPTKDM4E
SCHEMBL710621 0.79 TSHR (0.50) TYRTSHRCASP1PRKCIMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3646097-B1 FILLING COMPOSITION FOR OPTICAL FIBER CABLES DOW GLOBAL TECHNOLOGIES LLC (US) 2024-06-12 EP claimed
EP-3646096-B1 FILLING COMPOSITION FOR OPTICAL FIBER CABLES DOW GLOBAL TECHNOLOGIES LLC (US) 2024-02-07 EP claimed
EP-1309540-B1 OXIDIZING COLORANT HENKEL KGAA (DE) 2005-11-02 EP claimed
EP-1090813-B1 Expandable sealant composition containing a grafted olefinic polymer SIKA CORP (US) 2005-01-26 EP claimed
EP-1309540-A1 OXIDIZING COLORANT Henkel Kommanditgesellschaft auf Aktien (DE) 2003-05-14 EP claimed
WO-2002010118-A1 OXIDIZING COLORANT HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-02-07 WO claimed
EP-0796805-B1 Seal configuration for aerosol canister MINNESOTA MINING & MFG (US) 2000-01-05 EP claimed
EP-1309540-B1 OXIDIZING COLORANT HENKEL KGAA (DE) 2005-11-02 EP disclosed
EP-1309540-A1 OXIDIZING COLORANT Henkel Kommanditgesellschaft auf Aktien (DE) 2003-05-14 EP disclosed
WO-2002010118-A1 OXIDIZING COLORANT HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-02-07 WO disclosed