Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.44 |
| ▸ | CDK1 | P06493 | 3/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.44 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7271653 | 1.00 | MEN1 (0.55) | MEN1KMT2ACA1CA12CA9 | |
| SCHEMBL5669616 | 0.90 | MEN1 (0.47) | MEN1KMT2ACA1CA12CA9 | |
| SCHEMBL5669620 | 0.90 | MEN1 (0.47) | MEN1KMT2ACA1CA12CA9 | |
| SCHEMBL31492037 | 0.86 | LRRK2 (0.60) | CA1CA12CA9CA2LRRK2 | |
| SCHEMBL6939837 | 0.85 | MEN1 (0.44) | MEN1KMT2ACA1CA12CA9 | |
| SCHEMBL7269531 | 0.85 | MEN1 (0.44) | MEN1KMT2ACA1CA12CA9 | |
| SCHEMBL4895008 | 0.84 | KMT2A (0.52) | MEN1KMT2ALRRK2AGTR1HSP90AA1 | |
| SCHEMBL4895014 | 0.84 | KMT2A (0.52) | MEN1KMT2ALRRK2AGTR1HSP90AA1 | |
| SCHEMBL7263628 | 0.82 | KDR (0.53) | MEN1KMT2ACA1CA12CA9 | |
| SCHEMBL6941860 | 0.82 | KDR (0.53) | MEN1KMT2ACA1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230136466-A1 | BACTERIAL DNA GYRASE INHIBITORS AND METHODS OF USE THEREOF | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) | 2023-05-04 | — | — | US | disclosed |
| US-20030229453-A1 | Crystals and structures of PAK4KD kinase PAK4KD | SGX PHARMACEUTICALS, INC. | 2003-12-11 | — | — | US | disclosed |
| WO-2003087816-A1 | CRYSTALS AND STRUCTURES OF PAK4KD KINASE PAK4KD | STRUCTURAL GENOMIX, INC. (US) | 2003-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230136466-A1 | BACTERIAL DNA GYRASE INHIBITORS AND METHODS OF USE THEREOF | TOP1, DNA2, TOP2A | MEN1 4457/4885KMT2A 2037/4885CA1 4817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.