Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5353749 | 1.00 | LMNA (0.39) | LMNAALDH1A1MEN1KMT2ACYP4F2 | |
| SCHEMBL5352192 | 0.99 | MEN1 (0.39) | LMNAALDH1A1MEN1KMT2ACYP4F2 | |
| SCHEMBL7236425 | 0.99 | LMNA (0.40) | LMNAALDH1A1MEN1KMT2ACYP4F2 | |
| SCHEMBL7225770 | 0.91 | LMNA (0.36) | LMNAALDH1A1MEN1KMT2ACYP4F2 | |
| SCHEMBL7225893 | 0.90 | LMNA (0.37) | LMNAALDH1A1MEN1KMT2ACYP4F2 | |
| SCHEMBL5354722 | 0.86 | MEN1 (0.35) | LMNAALDH1A1MEN1KMT2ACYP4F2 | |
| SCHEMBL7220486 | 0.86 | MEN1 (0.35) | LMNAALDH1A1MEN1KMT2ACYP4F2 | |
| SCHEMBL4018595 | 0.84 | MEN1 (0.50) | LMNAALDH1A1MEN1KMT2ACYP4F2 | |
| SCHEMBL5857559 | 0.83 | CYP4F2 (0.55) | ALDH1A1MEN1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL5353382 | 0.82 | MEN1 (0.41) | ALDH1A1MEN1KMT2ACYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030092695-A1 | Metal salts of 3-methyl-chromane or thiochromane derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-05-15 | — | — | US | disclosed |
| EP-1240155-A4 | METAL SALTS OF 3-METHYL-CHROMANE OR THIOCHROMANE DERIVATIVES | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2003-04-16 | — | — | EP | disclosed |
| EP-1240155-A1 | METAL SALTS OF 3-METHYL-CHROMANE OR THIOCHROMANE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001042236-A1 | METAL SALTS OF 3-METHYL-CHROMANE OR THIOCHROMANE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092695-A1 | Metal salts of 3-methyl-chromane or thiochromane derivatives | NR5A1, SHBG, ESR1 | LMNA 3974/4885ALDH1A1 3711/4885MEN1 700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.