Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5354722 | 1.00 | MEN1 (0.35) | MEN1KMT2ACYP4F2CYP4A11HTT | |
| SCHEMBL7225893 | 0.96 | LMNA (0.37) | MEN1KMT2ACYP4F2CYP4A11HTT | |
| SCHEMBL7225770 | 0.95 | LMNA (0.36) | MEN1KMT2ACYP4F2CYP4A11HTT | |
| SCHEMBL7236425 | 0.87 | LMNA (0.40) | MEN1KMT2ACYP4F2CYP4A11HTT | |
| SCHEMBL6936029 | 0.86 | LMNA (0.39) | MEN1KMT2ACYP4F2CYP4A11HTT | |
| SCHEMBL5353749 | 0.86 | LMNA (0.39) | MEN1KMT2ACYP4F2CYP4A11HTT | |
| SCHEMBL5352192 | 0.84 | MEN1 (0.39) | MEN1KMT2ACYP4F2CYP4A11HTT | |
| SCHEMBL4018595 | 0.81 | MEN1 (0.50) | MEN1KMT2ACYP4F2CYP4A11HTT | |
| SCHEMBL7227354 | 0.79 | CPB2 (0.37) | CYP4F2CYP4A11LMNAALDH1A1MAPT | |
| SCHEMBL5350121 | 0.78 | CPB2 (0.38) | LMNAALDH1A1MAPTSMN1; SMN2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6552069-B1 | Having anti-estrogenic activity; for use in therapy | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-04-22 | — | — | US | disclosed |
| EP-1241166-A1 | 3-METHYL-CHROMAN AND -THIOCHROMAN DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-09-18 | — | — | EP | disclosed |