Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL673631 | 0.75 | CALM1 (0.50) | TSHRALDH1A1TP53CALM1IDO1 | |
| SCHEMBL10739452 | 0.72 | TP53 (0.50) | TSHRALDH1A1TP53CALM1IDO1 | |
| SCHEMBL28371008 | 0.71 | CALM1 (0.45) | TSHRALDH1A1TP53CALM1IDO1 | |
| SCHEMBL10736520 | 0.69 | MAOB (0.43) | TSHRALDH1A1TP53CALM1IDO1 | |
| SCHEMBL11054885 | 0.69 | CALM1 (0.43) | TSHRALDH1A1TP53CALM1IDO1 | |
| Ethylbenzene SCHEMBL1332452 | 0.65 | — | — | |
| Ethylbenzene SCHEMBL11223212 | 0.65 | TP53 (1.00) | TSHRALDH1A1TP53CALM1IDO1 | |
| Ethylbenzene SCHEMBL7458207 | 0.65 | TP53 (1.00) | TSHRALDH1A1TP53CALM1IDO1 | |
| Ethane SCHEMBL21049496 | 0.65 | ALDH1A1 (0.61) | ALDH1A1TP53CALM1LOXL2TDP1 | |
| Ethylbenzene SCHEMBL3987542 | 0.65 | TP53 (1.00) | TSHRALDH1A1TP53CALM1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103130793-A | 3-(1-aryl-piperidin-4-yl)-2-aryl-thiazole-4-ketone compound, preparation method thereof and use thereof | INST PHARM & TOXICOLOGY AMMS | 2013-06-05 | — | — | CN | claimed |
| CN-101863941-A | Derivative of 3-oxygen-substituted 6,11-di-oxygen-clarithromycin A | UNIV WUHAN | 2010-10-20 | — | — | CN | claimed |
| CN-101845069-A | Derivative of 4'-substituted 6,11-2-oxygen-carithromycin A | UNIV WUHAN | 2010-09-29 | — | — | CN | claimed |
| CN-103130793-A | 3-(1-aryl-piperidin-4-yl)-2-aryl-thiazole-4-ketone compound, preparation method thereof and use thereof | INST PHARM & TOXICOLOGY AMMS | 2013-06-05 | — | — | CN | disclosed |
| CN-102816138-A | Preparation method of paclitaxel derivative | INST MATERIA MEDICA CAMS | 2012-12-12 | — | — | CN | disclosed |
| CN-101062925-B | Taxol derivative, preparation method thereof, pharmaceutical composition thereof and application thereof | INST MATERIA MEDICA CAMS | 2012-08-22 | — | — | CN | disclosed |
| CN-101863941-A | Derivative of 3-oxygen-substituted 6,11-di-oxygen-clarithromycin A | UNIV WUHAN | 2010-10-20 | — | — | CN | disclosed |
| CN-101845069-A | Derivative of 4'-substituted 6,11-2-oxygen-carithromycin A | UNIV WUHAN | 2010-09-29 | — | — | CN | disclosed |
| CN-101062925-A | Taxol derivative, preparation method thereof, pharmaceutical composition thereof and application thereof | INST MATERIA MEDICA CAMS (CN) | 2007-10-31 | — | — | CN | disclosed |
| EP-0828195-B1 | Method for improving photoimage quality | CIBA SC HOLDING AG (CH) | 2003-02-19 | — | — | EP | disclosed |
| US-5912106-A | REDUCING POLYMERIZATION OF PHOTOCURABLE RESINS FOR IMAGES | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-06-15 | — | — | US | disclosed |
| CN-1176405-A | Method for improving photoimage quality | CIBA GEIGY AG (CH) | 1998-03-18 | — | — | CN | disclosed |
| EP-0828195-A2 | Method for improving photoimage quality | Ciba SC Holding AG (CH) | 1998-03-11 | — | — | EP | disclosed |