Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | IDO1 | P14902 | 3/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10736520 | 0.78 | MAOB (0.43) | CALM1TSHRALDH1A1IDO1LOXL2 | |
| SCHEMBL673631 | 0.73 | CALM1 (0.50) | CALM1TSHRALDH1A1IDO1LOXL2 | |
| SCHEMBL27669406 | 0.71 | CALM1 (0.47) | CALM1TSHRALDH1A1IDO1LOXL2 | |
| Iodide SCHEMBL27313116 | 0.71 | CALM1 (0.47) | CALM1TSHRALDH1A1IDO1LOXL2 | |
| SCHEMBL28371008 | 0.69 | CALM1 (0.45) | CALM1TSHRALDH1A1IDO1LOXL2 | |
| SCHEMBL6936265 | 0.69 | TSHR (0.48) | CALM1TSHRALDH1A1IDO1LOXL2 | |
| SCHEMBL9568181 | 0.69 | TP53 (0.41) | CALM1TSHRALDH1A1TP53HPGD | |
| SCHEMBL9747193 | 0.65 | TRPA1 (0.31) | TSHRALDH1A1TRPA1 | |
| SCHEMBL10739452 | 0.65 | TP53 (0.50) | CALM1TSHRALDH1A1IDO1LOXL2 | |
| SCHEMBL3891814 | 0.63 | ALDH1A1 (0.36) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4432970-A | SYNERGISTIC WITH AMINO ACID DERIVATIVE ANTIBIOTICS | PFIZER INC. (US) | 1984-02-21 | — | — | US | disclosed |