SCHEMBL6936880

SCHEMBL6936880

C=C[Si](Cl)(C=C)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
TSHR P16473 2/20 0.38
AKT1 P31749 1/20 0.31
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL388506 0.79 ALDH1A1 (0.38) ALDH1A1TSHRAKT1ESR1ESR2
SCHEMBL296342 0.79 ALDH1A1 (0.38) ALDH1A1TSHRAKT1ESR1ESR2
SCHEMBL9064101 0.75 ALDH1A1 (0.40) ALDH1A1TSHR
SCHEMBL296774 0.75 ESR1 (0.37) ALDH1A1TSHRESR1ESR2
SCHEMBL15302071 0.74 ALDH1A1 (0.38) ALDH1A1TSHRAKT1ESR1ESR2
SCHEMBL1674781 0.72 ALDH1A1 (0.41) ALDH1A1TSHRAKT1ESR1ESR2
SCHEMBL160241 0.72 ALDH1A1 (0.41) ALDH1A1TSHRAKT1ESR1ESR2
SCHEMBL226240 0.72 ALDH1A1 (0.41) ALDH1A1TSHRAKT1ESR1ESR2
SCHEMBL2268083 0.70 ALDH1A1 (0.31) ALDH1A1TSHR
SCHEMBL2101781 0.70 TSHR (0.31) ALDH1A1TSHRAKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113185751-A Halogen-free silicon flame-retardant vinyl resin, preparation method thereof and application thereof in copper-clad plate 艾蒙特成都新材料科技有限公司 2021-07-30 CN claimed
CN-103242534-B Anti-structuring control agent of white carbon black filling silicon rubber and preparation method of agent JIANGSU QIXIANG HIGH NEW MATERIAL CO LTD 2015-04-15 CN claimed
CN-103242534-A Anti-structuring control agent of white carbon black filling silicon rubber and preparation method of agent JIANGSU QIXIANG NEW MATERIAL CO LTD 2013-08-14 CN claimed
EP-0954543-B1 NOVEL PROCESS FOR DECOMPOSING SILOXANE BOND-CONTAINING COMPOUND YANG JAE KUN (KR) 2003-07-16 EP claimed
JP-2000508026-A 2000-06-27 JP claimed
EP-0954543-A1 NOVEL PROCESS FOR DECOMPOSING SILOXANE BOND-CONTAINING COMPOUND Yang, Jae-kun (KR) 1999-11-10 EP claimed
US-5892087-A Process for decomposing siloxane bond-containing compound Yang, Jae-Kun (KR) 1999-04-06 US claimed
WO-1998031726-A1 NOVEL PROCESS FOR DECOMPOSING SILOXANE BOND-CONTAINING COMPOUND YANG JAE KUN (KR) 1998-07-23 WO claimed
US-20260001974-A1 DISULFUR DICHLORIDE AND SILANE/SILOXANE ADDITIVE FOR MOONEY JUMP GOODYEAR TIRE & RUBBER (US) 2026-01-01 US disclosed
WO-2024092881-A1 HIGH- AND LOW-TEMPERATURE RESISTANT, ANTI-VIBRATION AND THERMAL-INSULATION MATERIAL, AND PREPARATION METHOD THEREFOR 北京宇航系统工程研究所 2024-05-10 WO disclosed
CN-113185751-A Halogen-free silicon flame-retardant vinyl resin, preparation method thereof and application thereof in copper-clad plate 艾蒙特成都新材料科技有限公司 2021-07-30 CN disclosed
CN-106967107-A The method for producing organo-silicon compound 道康宁东丽株式会社 2017-07-21 CN disclosed
US-9260458-B2 Method of producing an organic silicon compound DOW CORNING CORPORATION (US) 2016-02-16 US disclosed
US-20150141689-A1 Method Of Producing An Organic Silicon Compound DOW TORAY CO., LTD. (JP) 2015-05-21 US disclosed
US-5892087-A Process for decomposing siloxane bond-containing compound Yang, Jae-Kun (KR) 1999-04-06 US disclosed
US-5763540-A A FLEXIBILITY-IMPARTING AGENT COMPRISING A POLYSILOXANE-POLYCARBOSILANE COPOLYMER BASED ON DIVINYLSILANEDIOL AND A 1,4-BIS/DIALKYLHYDROXYSILYL/BENZENE; CURING; ELASTICITY; STRESS RELIEVING FOR PACKAGING OF MINIATURE SILICON CHIPS FUJITSU LIMITED (JP) 1998-06-09 US disclosed
EP-0432905-B1 Polysilphenylenesiloxane, production process thereof, and resist material and semiconductor device formed thereof FUJITSU LTD (JP) 1998-02-04 EP disclosed
US-5484687-A PHOTORESISTS, THREE-DIMENSIONAL, POLYSILSESQUIOXANES FUJITSU LIMITED (JP) 1996-01-16 US disclosed
US-5240813-A POLYSILPHENYLENESILOXANE, PRODUCTION PROCESS THEREOF, AND RESIST MATERIAL AND SEMICONDUCTOR DEVICE FORMED THEREOF FUJITSU LIMITED (JP) 1993-08-31 US disclosed
EP-0432905-A2 Polyisophenylenesiloxane, production process thereof, and resist material and semiconductor device formed thereof FUJITSU LIMITED (JP) 1991-06-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260001974-A1 DISULFUR DICHLORIDE AND SILANE/SILOXANE ADDITIVE FOR MOONEY JUMP DCLRE1A, DDR1, FDFT1 ALDH1A1 2993/4885TSHR 1187/4885AKT1 3017/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.