SCHEMBL296774

SCHEMBL296774

C=C[Si](C)(Cl)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
ALDH1A1 P00352 2/20 0.35
TSHR P16473 1/20 0.35
MAPT P10636 1/20 0.33
HDAC8 Q9BY41 1/20 0.31
NR1H2 P55055 1/20 0.31
NR1H3 Q13133 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10339557 0.80 ESR1 (0.39) ESR1ESR2ALDH1A1TSHRMAPT
SCHEMBL31231937 0.79 TDP1 (0.36) ALDH1A1MAPTNR1H2NR1H3
SCHEMBL31231932 0.77 NR1H2 (0.35) TSHRNR1H2NR1H3
SCHEMBL4530855 0.76 NR1H2 (0.46) ESR1ESR2ALDH1A1TSHRMAPT
SCHEMBL6936880 0.75 ALDH1A1 (0.38) ESR1ESR2ALDH1A1TSHR
SCHEMBL388506 0.75 ALDH1A1 (0.38) ESR1ESR2ALDH1A1TSHR
SCHEMBL296342 0.75 ALDH1A1 (0.38) ESR1ESR2ALDH1A1TSHR
SCHEMBL453982 0.75 NR1H2 (0.48) ESR1ESR2ALDH1A1TSHRMAPT
SCHEMBL2524118 0.75 ESR1 (0.39) ESR1ESR2ALDH1A1TSHRMAPT
SCHEMBL160355 0.75 ESR1 (0.39) ESR1ESR2ALDH1A1TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 750 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3927782-B1 AN ANTI-RUST COMPOSITION FOR METAL SURFACE AND A METHOD OF ANTI-RUST TREATMENT ON METAL SURFACE CHEMETALL GMBH (DE) 2026-04-08 EP claimed
CN-119285281-A Waterproof material for building outer wall and preparation method thereof 宁夏和兴元建设工程有限公司 2025-01-10 CN claimed
CN-118684929-B Continuous preparation process of PFA composite copper foil coil 苏州浅米科技有限公司 2024-12-03 CN claimed
CN-118684929-A Continuous preparation process of PFA composite copper foil coil 苏州浅米科技有限公司 2024-09-24 CN claimed
CN-116589806-B Polyvinyl chloride composite material and preparation method thereof 安庆市悦发管业有限公司 2024-07-30 CN claimed
US-12006445-B2 Anti-rust composition for metal surface and a method of anti-rust treatment on metal surface CHEMETALL GMBH (DE) 2024-06-11 US claimed
CN-109678171-B Ti-MWW molecular sieve with high external surface area and high framework titanium content, and preparation method and catalytic application thereof 中国石油化工股份有限公司 2024-03-29 CN claimed
CN-117050393-A High-elastic wear-resistant rubber backing plate and preparation method thereof 台州大华铁路材料有限公司 2023-11-14 CN claimed
CN-116589806-A Novel polyvinyl chloride composite material and preparation method thereof 安庆市悦发管业有限公司 2023-08-15 CN claimed
CN-113801303-B Method and device for preparing polylactic acid 北京工商大学 2023-07-18 CN claimed
US-20070087025-A1 Reiteratively layered medical devices and method of preparing same FITZHUGH ANTHONY 2007-04-19 US claimed
WO-2006062219-A1 ULTRAVIOLET TRANSMISSIVE POLYHEDRAL SILSESQUIOXANE POLYMERS MATSUSHITA ELECTRIC WORKS, LTD. (JP) 2006-06-15 WO claimed
US-20060122351-A1 Ultraviolet transmissive polyhedral silsesquioxane polymers PANASONIC ELECTRIC WORKS CO., LTD. (JP) 2006-06-08 US claimed
EP-1436018-A1 NITRIC OXIDE-RELEASING COATED MEDICAL DEVICES AND METHOD OF PREPARING SAME THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2004-07-14 EP claimed
EP-0954543-B1 NOVEL PROCESS FOR DECOMPOSING SILOXANE BOND-CONTAINING COMPOUND YANG JAE KUN (KR) 2003-07-16 EP claimed
WO-2003026717-A1 NITRIC OXIDE-RELEASING COATED MEDICAL DEVICES AND METHOD OF PREPARING SAME THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2003-04-03 WO claimed
JP-2000508026-A 2000-06-27 JP claimed
EP-0954543-A1 NOVEL PROCESS FOR DECOMPOSING SILOXANE BOND-CONTAINING COMPOUND Yang, Jae-kun (KR) 1999-11-10 EP claimed
US-5892087-A Process for decomposing siloxane bond-containing compound Yang, Jae-Kun (KR) 1999-04-06 US claimed
WO-1998031726-A1 NOVEL PROCESS FOR DECOMPOSING SILOXANE BOND-CONTAINING COMPOUND YANG JAE KUN (KR) 1998-07-23 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070087025-A1 Reiteratively layered medical devices and method of preparing same NOS2, NOS1, NOS3 ESR1 1016/4885ESR2 1178/4885ALDH1A1 2127/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.