Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6935943 | 0.83 | NR1H4 (0.49) | FFAR4LMNAALDH1A1PTPN1 | |
| SCHEMBL4600718 | 0.77 | CYP4F2 (0.50) | CYP4F2CYP4A11KDM4EGAALMNA | |
| SCHEMBL304455 | 0.73 | CYP4F2 (0.74) | CYP4F2CYP4A11KDM4EGAAKMT2A | |
| Ethane SCHEMBL27846059 | 0.71 | CYP4F2 (0.72) | CYP4F2CYP4A11KDM4EGAAKMT2A | |
| SCHEMBL1826425 | 0.71 | GABRA1 (0.39) | CYP4F2CYP4A11KDM4EGAAMAPT | |
| SCHEMBL1900966 | 0.69 | MEN1 (0.71) | KDM4EMAPTKMT2AALDH1A1 | |
| SCHEMBL435053 | 0.69 | CYP4F2 (0.68) | CYP4F2CYP4A11KMT2ACA12CA1 | |
| SCHEMBL5542112 | 0.69 | CYP4Z1 (0.60) | CYP4F2CYP4A11KDM4EGAALMNA | |
| SCHEMBL5545488 | 0.68 | CYP4Z1 (0.59) | CYP4F2CYP4A11KDM4EGAALMNA | |
| SCHEMBL11615189 | 0.68 | CYP4Z1 (0.59) | CYP4F2CYP4A11KDM4EGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0916651-B1 | PHENYLALKYLCARBOXYLIC ACID DERIVATIVES | SANKYO CO (JP) | 2003-10-15 | — | — | EP | disclosed |
| US-6103907-A | ALDOSE REDUCTASE INHIBITING ANTIDIABETIC AGENT | SANKYO COMPANY, LIMITED (JP) | 2000-08-15 | — | — | US | disclosed |
| CN-1219927-A | Phenylalkylcarboxylic acid derivatives | SANKYO CO (JP) | 1999-06-16 | — | — | CN | disclosed |
| EP-0916651-A1 | PHENYLALKYLCARBOXYLIC ACID DERIVATIVES | Sankyo Company, Limited (JP) | 1999-05-19 | — | — | EP | disclosed |