Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | LTA4H | P09960 | 3/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6936992 | 0.83 | FFAR4 (0.46) | LMNAFFAR4ALDH1A1PTPN1 | |
| SCHEMBL3091164 | 0.81 | FFAR1 (0.68) | NR1H4L3MBTL1LMNAFFAR4ALDH1A1 | |
| SCHEMBL8561154 | 0.78 | L3MBTL1 (0.50) | NR1H4L3MBTL1LMNAALDH1A1FAAH | |
| SCHEMBL8890454 | 0.77 | FFAR1 (0.59) | NR1H4L3MBTL1LMNAFFAR4ALDH1A1 | |
| SCHEMBL1115103 | 0.77 | LTA4H (0.65) | NR1H4L3MBTL1LMNAALDH1A1LTA4H | |
| SCHEMBL2773462 | 0.77 | FFAR1 (0.68) | NR1H4L3MBTL1LMNAFFAR4ALDH1A1 | |
| SCHEMBL8888760 | 0.76 | FFAR1 (0.58) | NR1H4L3MBTL1LMNAFFAR4ALDH1A1 | |
| SCHEMBL8887581 | 0.76 | FFAR1 (0.58) | NR1H4L3MBTL1LMNAFFAR4ALDH1A1 | |
| SCHEMBL8890073 | 0.76 | FFAR1 (0.58) | NR1H4L3MBTL1LMNAFFAR4ALDH1A1 | |
| SCHEMBL19825762 | 0.76 | FFAR1 (0.61) | NR1H4L3MBTL1LMNAFFAR4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0916651-B1 | PHENYLALKYLCARBOXYLIC ACID DERIVATIVES | SANKYO CO (JP) | 2003-10-15 | — | — | EP | disclosed |
| US-6103907-A | ALDOSE REDUCTASE INHIBITING ANTIDIABETIC AGENT | SANKYO COMPANY, LIMITED (JP) | 2000-08-15 | — | — | US | disclosed |
| CN-1219927-A | Phenylalkylcarboxylic acid derivatives | SANKYO CO (JP) | 1999-06-16 | — | — | CN | disclosed |
| EP-0916651-A1 | PHENYLALKYLCARBOXYLIC ACID DERIVATIVES | Sankyo Company, Limited (JP) | 1999-05-19 | — | — | EP | disclosed |