Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 6/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | TACR2 | P21452 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6939785 | 0.88 | SLC6A2 (0.41) | OPRL1SLC6A4SLC6A3SLC6A2CCR1 | |
| SCHEMBL6936962 | 0.86 | SLC6A4 (0.40) | OPRL1UTS2RSLC6A4SLC6A3SLC6A2 | |
| SCHEMBL5846308 | 0.86 | CCR5 (0.38) | OPRL1SLC6A4SLC6A3SLC6A2CCR1 | |
| Hydrochloric Acid SCHEMBL5847559 | 0.85 | CCR5 (0.37) | OPRL1SLC6A4SLC6A3SLC6A2CCR1 | |
| SCHEMBL6939057 | 0.82 | SLC6A4 (0.42) | OPRL1UTS2RSLC6A4SLC6A3SLC6A2 | |
| SCHEMBL6934438 | 0.81 | OPRK1 (0.40) | SLC6A4SLC6A2 | |
| SCHEMBL6937455 | 0.80 | PSEN1 (0.37) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL6939734 | 0.80 | SLC6A3 (0.35) | SLC6A4SLC6A3SLC6A2TRPA1TACR2 | |
| SCHEMBL6939083 | 0.79 | SLC6A2 (0.41) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL6937438 | 0.79 | SLC6A2 (0.41) | OPRL1SLC6A4SLC6A3SLC6A2TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043307-B1 | 3-amino-3-arylpropan-1-ol-derivates, their preparation and their use | GRUENENTHAL GMBH (DE) | 2003-06-04 | — | — | EP | disclosed |