Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 13/20 | 0.49 |
| ▸ | RARA | P10276 | 2/20 | 0.49 |
| ▸ | RARG | P13631 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6936303 | 1.00 | RARB (0.49) | RARBRARARARGALDH1A1MEN1 | |
| SCHEMBL6939655 | 0.90 | RARB (0.50) | RARBALDH1A1MMP2MMP12HPGD | |
| SCHEMBL6939565 | 0.86 | HDAC3 (0.43) | RARBRARARARGALDH1A1MAPT | |
| SCHEMBL6939762 | 0.86 | HDAC3 (0.43) | RARBRARARARGALDH1A1MAPT | |
| SCHEMBL7920844 | 0.82 | RARB (0.51) | RARBRARARARGALDH1A1MEN1 | |
| SCHEMBL6936308 | 0.80 | MMP2 (0.67) | RARBRARAALDH1A1MEN1MAPT | |
| SCHEMBL2835265 | 0.79 | RAB9A (0.44) | RARBALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL2835012 | 0.77 | ALDH1A1 (0.45) | RARBALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL30143434 | 0.76 | MMP2 (0.72) | RARBRARAALDH1A1MEN1MAPT | |
| SCHEMBL6934491 | 0.76 | MMP2 (0.72) | RARBRARAALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0962445-B1 | Acetylene compound, liquid crystal composition and liquid crystal element | MITSUI CHEMICALS INC (JP) | 2003-02-26 | — | — | EP | disclosed |
| EP-0962445-A1 | Acetylene compound, liquid crystal composition and liquid crystal element | Mitsui Chemicals, Inc. (JP) | 1999-12-08 | — | — | EP | disclosed |