Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | GBA1 | P04062 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8863060 | 1.00 | EPHX1 (0.37) | EPHX1SMN1; SMN2CYP2D6TSHRCHRNA7 | |
| SCHEMBL8476572 | 1.00 | EPHX1 (0.37) | EPHX1SMN1; SMN2CYP2D6TSHRCHRNA7 | |
| SCHEMBL8482165 | 0.84 | CYP2D6 (0.46) | SMN1; SMN2CYP2D6TSHRGAAPOLB | |
| SCHEMBL6937090 | 0.76 | CHRNA7 (0.42) | EPHX1SMN1; SMN2CYP2D6TSHRCHRNA7 | |
| SCHEMBL7836631 | 0.67 | ALDH1A1 (0.51) | SMN1; SMN2CYP2D6TSHRMEN1KMT2A | |
| SCHEMBL15713298 | 0.67 | ALDH1A1 (0.51) | SMN1; SMN2CYP2D6TSHRMEN1KMT2A | |
| SCHEMBL18091184 | 0.67 | ALDH1A1 (0.51) | SMN1; SMN2CYP2D6TSHRMEN1KMT2A | |
| SCHEMBL7836638 | 0.67 | ALDH1A1 (0.51) | SMN1; SMN2CYP2D6TSHRMEN1KMT2A | |
| SCHEMBL4729434 | 0.66 | MEN1 (0.43) | CYP2D6MEN1KMT2AEDNRAGAA | |
| SCHEMBL4729436 | 0.66 | MEN1 (0.43) | CYP2D6MEN1KMT2AEDNRAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1097044-C | Taxane derivatives and drugs contg. same | YAKULT HONSHA KK (JP) | 2002-12-25 | — | — | CN | disclosed |
| US-6025385-A | HIGH SOLUBILITY IN WATER AND ALSO HAS EXCELLENT ANTITUMOR ACTIVITIES. | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2000-02-15 | — | — | US | disclosed |
| CN-1225633-A | Taxane derivatives and drugs containing the same | YAKULT HONSHA KK (JP) | 1999-08-11 | — | — | CN | disclosed |
| EP-0930309-A1 | TAXANE DERIVATIVES AND DRUGS CONTAINING THE SAME | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1999-07-21 | — | — | EP | disclosed |