Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 4/20 | 0.56 |
| ▸ | PLG | P00747 | 4/20 | 0.56 |
| ▸ | F2 | P00734 | 2/20 | 0.56 |
| ▸ | PLAT | P00750 | 2/20 | 0.56 |
| ▸ | F10 | P00742 | 1/20 | 0.56 |
| ▸ | SRC | P12931 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | KLK1 | P06870 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.53 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6936149 | 1.00 | PLAU (0.56) | PLAUPLGF2PLATF10 | |
| SCHEMBL6575251 | 0.92 | PLAU (0.64) | PLAUPLGF2PLATF10 | |
| SCHEMBL3925183 | 0.85 | PLG (0.62) | PLAUPLGF2PLATF10 | |
| SCHEMBL3914853 | 0.85 | PLAU (0.62) | PLAUPLGF2PLATF10 | |
| SCHEMBL8480342 | 0.85 | PLAU (0.62) | PLAUPLGF2PLATF10 | |
| Hydrochloric Acid SCHEMBL3922499 | 0.84 | PLG (0.61) | PLAUPLGF2PLATF10 | |
| Hydrochloric Acid SCHEMBL3922301 | 0.84 | PLAU (0.61) | PLAUPLGF2PLATF10 | |
| SCHEMBL8479137 | 0.84 | PLG (0.62) | PLAUPLGF2PLATF10 | |
| SCHEMBL8481738 | 0.84 | PLG (0.62) | PLAUPLGF2PLATF10 | |
| SCHEMBL3922492 | 0.83 | PLG (0.60) | PLAUPLGF2PLATF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882705-B1 | BIS(AMINOCARBONYLNAPHTHOL) DERIVATIVE | UENO SEIYAKU OYO KENKYUJO KK (JP) | 2003-05-28 | — | — | EP | disclosed |
| US-6072042-A | Bis(aminocarbonylnaphthol) derivative | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2000-06-06 | — | — | US | disclosed |
| EP-0882705-A1 | BIS(AMINOCARBONYLNAPHTHOL) DERIVATIVE | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1998-12-09 | — | — | EP | disclosed |