Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 3/20 | 0.62 |
| ▸ | F2 | P00734 | 2/20 | 0.59 |
| ▸ | PLG | P00747 | 2/20 | 0.59 |
| ▸ | PLAT | P00750 | 2/20 | 0.59 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.59 |
| ▸ | KLK1 | P06870 | 1/20 | 0.59 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.59 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.58 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.56 |
| ▸ | F10 | P00742 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | SRC | P12931 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3922301 | 0.99 | PLAU (0.61) | PLAUF2PLGPLATKLKB1 | |
| SCHEMBL7047835 | 0.94 | PLAU (0.59) | PLAUF2PLGPLATKLKB1 | |
| SCHEMBL6575251 | 0.93 | PLAU (0.64) | PLAUF2PLGPLATKLKB1 | |
| SCHEMBL3922289 | 0.89 | PLAU (0.59) | PLAUF2PLGPLATKLKB1 | |
| SCHEMBL3925183 | 0.89 | PLG (0.62) | PLAUF2PLGPLATKLKB1 | |
| Hydrochloric Acid SCHEMBL3922499 | 0.87 | PLG (0.61) | PLAUF2PLGPLATKLKB1 | |
| SCHEMBL6938709 | 0.87 | MEN1 (0.58) | PTPN11KMT2ANPC1RAB9ASRC | |
| SCHEMBL6936149 | 0.85 | PLAU (0.56) | PLAUF2PLGPLATKLKB1 | |
| SCHEMBL8480342 | 0.85 | PLAU (0.62) | PLAUF2PLGPLATKLKB1 | |
| SCHEMBL6937149 | 0.85 | PLAU (0.56) | PLAUF2PLGPLATKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7531691-B2 | Method for producing naphthalene carboxylic acid amide compound | UENO FINE CHEMICALS INDUSTRY, LTD. (JP) | 2009-05-12 | — | — | US | disclosed |
| US-20080045720-A1 | Method for producing naphthalene carboxylic acid amide compound | UENO FINE CHEMICALS INDUSTRY, LTD. (JP) | 2008-02-21 | — | — | US | disclosed |
| EP-1867629-A2 | Method for producing naphthalene carboxylic acid amide compound | Ueno Fine Chemicals Industry, Ltd. (JP) | 2007-12-19 | — | — | EP | disclosed |
| CN-101088987-A | Method for producing naphthalene carboxylic acid amide compound | UENO FINE CHEMICAL IND (JP) | 2007-12-19 | — | — | CN | disclosed |
| US-7169523-B2 | electrophotographic toners comprising binder resins, colorants and charge control agents consisting of naphthol derivatives, having excellent negative chargeability, dispersion in and compatibility with binders | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2007-01-30 | — | — | US | disclosed |
| US-7169523-B2 | electrophotographic toners comprising binder resins, colorants and charge control agents consisting of naphthol derivatives, having excellent negative chargeability, dispersion in and compatibility with binders | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2007-01-30 | — | — | US | disclosed |
| EP-0937753-B1 | WATER-SOLUBLE AZO COMPOUNDS AND PROCESS FOR PRODUCING THE SAME | UENO SEIYAKU OYO KENKYUJO KK (JP) | 2003-08-06 | — | — | EP | disclosed |
| EP-0882705-B1 | BIS(AMINOCARBONYLNAPHTHOL) DERIVATIVE | UENO SEIYAKU OYO KENKYUJO KK (JP) | 2003-05-28 | — | — | EP | disclosed |
| US-6548703-B1 | Toning agent | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2003-04-15 | — | — | US | disclosed |
| US-6239263-B1 | PREPARED FROM A COUPLER CONSISTING OF 2-HYDROXYNAPHTHALENE-3,6-DICARBOXYLIC ACID OR AN ESTER THEREOF OR AN AMIDE DERIVATIVE OF THE SAME AND A DIAZONIUM COMPOUND | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2001-05-29 | — | — | US | disclosed |
| EP-1043364-A1 | TONING AGENT | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2000-10-11 | — | — | EP | disclosed |
| US-6072042-A | Bis(aminocarbonylnaphthol) derivative | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2000-06-06 | — | — | US | disclosed |
| EP-0984042-A1 | WATER-SOLUBLE AZO COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 2000-03-08 | — | — | EP | disclosed |
| US-6020470-A | Water-soluble azo compounds and process for producing the same | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2000-02-01 | — | — | US | disclosed |
| US-5973126-A | REACTING A 2-HYDROXYNAPHTHALENE-3,6-DICARBOXYLIC ACID, AN AMIDE, OR AN ESTER THEREOF OR DERIVATIVES WITH A DIAZOTIZED AROMATIC PRIMARY AMINE; WATER RESISTANCE, CHEMICAL RESISTANCE AND SOLVENT RESISTANCE. | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1999-10-26 | — | — | US | disclosed |
| US-5965715-A | Bisazo compounds and process for the preparation thereof | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1999-10-12 | — | — | US | disclosed |
| EP-0937753-A1 | WATER-SOLUBLE AZO COMPOUNDS AND PROCESS FOR PRODUCING THE SAME | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1999-08-25 | — | — | EP | disclosed |
| EP-0882705-A1 | BIS(AMINOCARBONYLNAPHTHOL) DERIVATIVE | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1998-12-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045720-A1 | Method for producing naphthalene carboxylic acid amide compound | NAAA, AADAC, NAT1 | PLAU 4306/4885F2 2706/4885PLG 4202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.