SCHEMBL6937335

SCHEMBL6937335

CCSCC[C@@H](N)C(O)C(=O)N(N)C(=O)c1ccc(C(C)C)cc1

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 20/20 0.46
METAP1 P53582 12/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6939440 0.88 METAP2 (0.56) METAP2METAP1
SCHEMBL6937626 0.85 METAP2 (0.47) METAP2METAP1
SCHEMBL7308710 0.83 METAP2 (0.64) METAP2METAP1
SCHEMBL6942554 0.81 METAP2 (0.45) METAP2METAP1
SCHEMBL6563019 0.80 METAP2 (0.54) METAP2METAP1
SCHEMBL6564913 0.80 METAP2 (0.53) METAP2METAP1
SCHEMBL7075750 0.78 METAP2 (0.49) METAP2METAP1
SCHEMBL6489935 0.77 METAP2 (0.71) METAP2METAP1
SCHEMBL6565042 0.77 METAP2 (0.51) METAP2METAP1
SCHEMBL6940131 0.76 METAP2 (0.50) METAP2METAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1272456-A1 HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS Abbott Laboratories (US) 2003-01-08 EP claimed
WO-2001079157-A1 HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS ABBOTT LABORATORIES (US) 2001-10-25 WO claimed