Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA4 | P22748 | 4/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | PTPRG | P23470 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6937373 | 0.88 | KMT2A (0.70) | KMT2AL3MBTL1POLBMEN1ALDH1A1 | |
| SCHEMBL7136041 | 0.76 | KMT2A (0.58) | KMT2AL3MBTL1POLBMEN1ALDH1A1 | |
| SCHEMBL27576529 | 0.75 | KMT2A (0.70) | KMT2AL3MBTL1POLBMEN1ALDH1A1 | |
| SCHEMBL11352440 | 0.75 | KMT2A (0.47) | KMT2AL3MBTL1POLBMEN1ALDH1A1 | |
| SCHEMBL6291181 | 0.74 | KMT2A (0.60) | KMT2AL3MBTL1POLBMEN1ALDH1A1 | |
| SCHEMBL292247 | 0.74 | KMT2A (0.61) | KMT2AL3MBTL1POLBMEN1ALDH1A1 | |
| SCHEMBL11729716 | 0.74 | KMT2A (0.64) | KMT2AL3MBTL1POLBMEN1ALDH1A1 | |
| SCHEMBL1901284 | 0.74 | PTPRG (0.67) | KMT2AL3MBTL1POLBMEN1ALDH1A1 | |
| SCHEMBL15953118 | 0.74 | POLB (0.55) | KMT2AL3MBTL1POLBMEN1ALDH1A1 | |
| SCHEMBL9764561 | 0.73 | KMT2A (0.68) | KMT2AL3MBTL1POLBMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888332-B1 | N-Azacycloalkyl Alkyl Dibenzothiophene Carboxamides: Dopamine Receptor Subtype Specific Ligands | NEUROGEN CORP (US) | 2001-05-30 | — | — | EP | claimed |