Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 15/20 | 0.49 |
| ▸ | ACLY | P53396 | 3/20 | 0.48 |
| ▸ | KMO | O15229 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6940404 | 0.89 | ADA (0.47) | ADAACLY | |
| SCHEMBL6941810 | 0.87 | ADA (0.69) | ADAMCL1 | |
| SCHEMBL6938261 | 0.86 | LMNA (0.45) | ADA | |
| SCHEMBL6939011 | 0.84 | ADA (0.66) | ADAMCL1 | |
| SCHEMBL6939006 | 0.83 | ADA (0.48) | ADAACLYKMOMCL1 | |
| SCHEMBL6936378 | 0.79 | ADA (0.67) | ADA | |
| SCHEMBL5673460 | 0.78 | ADA (0.50) | ADA | |
| SCHEMBL6937608 | 0.77 | ADA (0.55) | ADA | |
| SCHEMBL6133743 | 0.76 | ADA (0.47) | ADAMCL1 | |
| SCHEMBL6133844 | 0.76 | ADA (0.38) | ADAACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596738-B1 | Inhibiting activity to adenosine deaminase (hereinafter described as ADA) An adenosine deaminase inhibiting agent comprising a compound of the formula (I): | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-22 | — | — | US | disclosed |