Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ADA | P00813 | 13/20 | 0.43 |
| ▸ | AGER | Q15109 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 4/20 | 0.43 |
| ▸ | CCND1 | P24385 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6940404 | 0.87 | ADA (0.47) | ADA | |
| SCHEMBL6937612 | 0.86 | ADA (0.49) | ADA | |
| SCHEMBL6938445 | 0.83 | ADA (0.51) | LMNAADACDK4CCND1 | |
| SCHEMBL6939156 | 0.83 | ADA (0.46) | LMNAADACDK4CCND1 | |
| SCHEMBL6941444 | 0.82 | KMO (0.44) | LMNAADA | |
| SCHEMBL6939011 | 0.82 | ADA (0.66) | ADA | |
| SCHEMBL6936378 | 0.80 | ADA (0.67) | LMNAADA | |
| SCHEMBL6940438 | 0.79 | MAPT (0.46) | LMNA | |
| SCHEMBL6940662 | 0.78 | ADA (0.71) | ADA | |
| SCHEMBL6941810 | 0.78 | ADA (0.69) | ADA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596738-B1 | Inhibiting activity to adenosine deaminase (hereinafter described as ADA) An adenosine deaminase inhibiting agent comprising a compound of the formula (I): | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-22 | — | — | US | disclosed |